Subdural effusion in a CNS involvement of systemic juvenile xanthogranuloma:: A case report treated with vinblastin

被引：16

作者：

Auvin, Stephane ^{[1
]}

Cuvellier, Jean-Christophe ^{[1
]}

Vinchon, Mathieu ^{[2
]}

Defoort-Dhellemes, Sabine ^{[3
]}

Soto-Ares, Gustavo ^{[4
]}

Nelken, Brigitte ^{[5
]}

Vallee, Louis ^{[1
]}

机构：

[1] Univ Hosp, Dept Pediat Neurol, Lille, France

[2] Univ Hosp, Dept Pediat Neurosurg, Lille, France

[3] Univ Hosp, Dept Ophthalmol, Lille, France

[4] Univ Hosp, Dept Neuroradiol, Lille, France

[5] Univ Hosp, Dept Pediat Hematooncol, Lille, France

来源：

BRAIN & DEVELOPMENT | 2008年 / 30卷 / 02期

关键词：

xanthogranuloma; subdural effusion; vinblastin; MANIFESTATIONS;

D O I：

10.1016/j.braindev.2007.07.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Juvenile xanthogranuloma (JXG) is one of the most common non-Langerhans cell histiocytosis in children. Usually cutaneous, there are disseminated forms. However, neurological localization remains exceptional. A 7-month-old boy had been admitted for subdural effusion due to non-accidental head injury and skin nodular lesions. A biopsy of a skin lesion was considered suggestive of JXG. Skin, eyes, brain, lungs, liver, and testicles were involved. Systemic treatment of JXG was begun with vinblastine. It allowed the regression of skin, lung, and CNS lesions. At age of 11 years, lie had not reappearance of the xanthogranuloma. This report emphasizes the possible presentation of xanthogranuloma with subdural effusions, the organs which should be examined in case of disseminated forms and the efficiency of vinblastin. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：164 / 168

页数：5

共 11 条

[1] Multiple intracranial juvenile xanthogranulomas [J].