Mid-infrared fiber-coupled supercontinuum spectroscopic imaging using a tapered chalcogenide photonic crystal fiber

被引：0

作者：

Petersen, Christian Rosenberg ^{[1
]}

Prtljaga, Nikola ^{[2
]}

Farries, Mark ^{[2
]}

Ward, Jon ^{[2
]}

Napier, Bruce ^{[3
]}

Lloyd, Gavin Rhys ^{[4
]}

Nallala, Jayakrupakar ^{[5
]}

Stone, Nick ^{[5
]}

Bang, Ole ^{[1
,6
]}

机构：

[1] Tech Univ Denmark, DTU Foton, Orsteds Plads Bldg 343, DK-2800 Lyngby, Denmark

[2] Gooch & Housego, Broomhill Way, Torquay TQ2 2QL, England

[3] Vivid Components, Dr Rorig Damm 22, D-33102 Paderborn, Germany

[4] Gloucestershire Hosp NHS Fdn Trust, Biophoton Res Unit, Gloucester GL1 3NN, England

[5] Univ Exeter, Sch Phys & Astron, Biomed Phys, Stocker Rd, Exeter EX4 4QL, Devon, England

[6] NKT Photon AS, Blokken 84, DK-3460 Birkerod, Denmark

来源：

OPTICAL BIOPSY XVI: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS | 2018年 / 10489卷

关键词：

Supercontinuum; spectroscopic imaging; mid-infrared; tissue imaging; chalcogenide optical fiber; MU-M;

D O I：

10.1117/12.2288541

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present the first demonstration of mid-infrared spectroscopic imaging of human tissue using a fiber-coupled supercontinuum source spanning from 2-7.5 mu m. The supercontinuum was generated in a tapered large mode area chalcogenide photonic crystal fiber in order to obtain broad bandwidth, high average power, and single-mode output for good imaging properties. Tissue imaging was demonstrated in transmission by raster scanning over a sub-mm region of paraffinized colon tissue on CaF2 substrate, and the signal was measured using a fiber-coupled grating spectrometer. This demonstration has shown that we can distinguish between epithelial and surrounding connective tissues within a paraffinized section of colon tissue by imaging at discrete wavelengths related to distinct chemical absorption features.

引用

页数：6

共 9 条

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