Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination

被引：0

作者：

Jansen, Frans Herwig ^{[1
]}

机构：

[1] ACT Ion Afrique, Brussels, Belgium

来源：

MALARIA JOURNAL | 2011年 / 10卷

关键词：

PLASMODIUM-FALCIPARUM MALARIA; SULFADOXINE-PYRIMETHAMINE; PREGNANT-WOMEN; RESISTANCE; CHILDREN; TRIAL;

D O I：

10.1186/1475-2875-10-70

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Recent publications put a serious warning regarding the inefficacy of sulphadoxine-pyrimethamine (SP) for the intermittent preventive treatment of malaria in young children (IPTi). Recommendations for other therapies are being made. By using a different and better sulphonamide (sulphamethoxypyrazine), it is possible to manufacture fixed dose combination pills with artesunate and pyrimethamine. This combination permits a full therapy over 24 hours (dosing interval being 12 hours). It is recommended that this combination should be tested in future field studies of IPTi.

引用

页数：3

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