Analytical techniques for the detection of amphetamine-type substances in different matrices: A comprehensive review

被引：30

作者：

Dragan, Ana-Maria ^{[1
,2
]}

Parrilla, Marc ^{[2
,3
]}

Feier, Bogdan ^{[1
]}

Cristea, Cecilia ^{[1
]}

Oprean, Radu ^{[1
]}

De Wael, Karolien ^{[2
,3
]}

机构：

[1] Iuliu Hatieganu Univ Med & Pharm, Dept Analyt Chem & Instrumental Anal, Pasteur 6, Cluj Napoca, Romania

[2] Univ Antwerp, A Sense Lab, Groenenborgerlaan 171, B-2010 Antwerp, Belgium

[3] Univ Antwerp, NANOlab Ctr Excellence, Groenenborgerlaan 171, B-2010 Antwerp, Belgium

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2021年 / 145卷

关键词：

Amphetamine-type substances; MDMA; Detection methods; On-site testing; Portable devices; Drug seizures; Forensic analysis; ENHANCED RAMAN-SPECTROSCOPY; SINGLE-DROP MICROEXTRACTION; TANDEM MASS-SPECTROMETRY; LIQUID-PHASE MICROEXTRACTION; NEAR-INFRARED SPECTROSCOPY; CHEMICAL SPOT TESTS; CAPILLARY-ELECTROPHORESIS; HUMAN URINE; PSYCHOACTIVE SUBSTANCES; LATERAL FLOW;

D O I：

10.1016/j.trac.2021.116447

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This current review focuses on contributions to amphetamine-type substances (ATS) analysis. This type of synthetic illicit drugs has been increasingly present worldwide reaching 5% of the market on illicit drugs in 2019. The increment of their production in many clandestine laboratories and easy distribution among society are two of the main concerns towards the battle against synthetic drugs. Therefore, the first part of this review details the classification and mechanism of action of ATS in the human body. Second, the pharmacological and toxicological effects of ATS on human health are described to motivate the need of early detection of ATS. Subsequently, the most used laboratory-based and portable methods are presented and critically discussed along the review. Finally, a careful discussion on the advantages and disadvantages of portable techniques employed on the field are addressed as potential tools for on-site ATS detection by law enforcement officers. (c) 2021 Elsevier B.V. All rights reserved.

引用

页数：31

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