Mechanisms of neuronal degeneration in Alzheimer's disease

被引：927
作者：
Yankner, BA [1 ]
机构：
[1] CHILDRENS HOSP, DIV NEUROSCI, BOSTON, MA 02115 USA
来源：
NEURON | 1996年 / 16卷 / 05期
关键词：
D O I：
10.1016/S0896-6273(00)80115-4
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
[No abstract available]
引用
收藏
页码：921 / 932
页数：12
相关论文
共 179 条
[1]   ROLE OF ABNORMALLY PHOSPHORYLATED TAN IN THE BREAKDOWN OF MICROTUBULES IN ALZHEIMER-DISEASE [J].
ALONSO, AD ;
ZAIDI, T ;
GRUNDKEIQBAL, I ;
IQBAL, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (12) :5562-5566
[2]  
Alzheimer A., 1907, ALLG Z PSYCHIAT, V18, P177, DOI DOI 10.1002/CA.980080612
[3]   DEFINED NEUROFILAMENT, TAU-AMYLOID AND BETA-AMYLOID PRECURSOR PROTEIN EPITOPES DISTINGUISH ALZHEIMER FROM NON-ALZHEIMER SENILE PLAQUES [J].
ARAI, H ;
LEE, VMY ;
OTVOS, L ;
GREENBERG, BD ;
LOWERY, DE ;
SHARMA, SK ;
SCHMIDT, ML ;
TROJANOWSKI, JQ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (06) :2249-2253
[4]   GIANT MULTILEVEL CATION CHANNELS FORMED BY ALZHEIMER-DISEASE AMYLOID BETA-PROTEIN [A-BETA-P-(1-40)] IN BILAYER-MEMBRANES [J].
ARISPE, N ;
POLLARD, HB ;
ROJAS, E .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (22) :10573-10577
[5]   SOLUTION STRUCTURES OF BETA PEPTIDE AND ITS CONSTITUENT FRAGMENTS - RELATION TO AMYLOID DEPOSITION [J].
BARROW, CJ ;
ZAGORSKI, MG .
SCIENCE, 1991, 253 (5016) :179-182
[6]   THE CHOLINERGIC HYPOTHESIS OF GERIATRIC MEMORY DYSFUNCTION [J].
BARTUS, RT ;
DEAN, RL ;
BEER, B ;
LIPPA, AS .
SCIENCE, 1982, 217 (4558) :408-417
[7]   HYDROGEN-PEROXIDE MEDIATES AMYLOID-BETA PROTEIN TOXICITY [J].
BEHL, C ;
DAVIS, JB ;
LESLEY, R ;
SCHUBERT, D .
CELL, 1994, 77 (06) :817-827
[8]   PHOSPHORYLATION OF SER(262) STRONGLY REDUCES BINDING OF TAU-PROTEIN TO MICROTUBULES - DISTINCTION BETWEEN PHF-LIKE IMMUNOREACTIVITY AND MICROTUBULE-BINDING [J].
BIERNAT, J ;
GUSTKE, N ;
DREWES, G ;
MANDELKOW, EM ;
MANDELKOW, E .
NEURON, 1993, 11 (01) :153-163
[9]  
BLASS JP, 1993, NEUROLOGY, V43, pS25
[10]   ABNORMAL TAU-PHOSPHORYLATION AT SER(396) IN ALZHEIMERS-DISEASE RECAPITULATES DEVELOPMENT AND CONTRIBUTES TO REDUCED MICROTUBULE-BINDING [J].
BRAMBLETT, GT ;
GOEDERT, M ;
JAKES, R ;
MERRICK, SE ;
TROJANOWSKI, JQ ;
LEE, VMY .
NEURON, 1993, 10 (06) :1089-1099
12345678910