Mechanisms of Antiradical Activity of 2,3,5,6,8-Pentahydroxy-7-Ethyl-1,4-Naphthoquinone (A Review)

被引：3
|
作者：
Talalaeva, O. S. [1 ]
Zverev, Ya F. [1 ]
Bryukhanov, V. M. [1 ]
机构：
[1] Altai State Med Univ, Minist Hlth Russian Federat, Barnaul 656038, Altai Krai, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2016年 / 50卷 / 06期
关键词：
polyphenols; antioxidants; echinochrome A; ANTIOXIDANT ACTIVITY; SCAVENGING ACTIVITIES; PIGMENT ECHINOCHROME; LIPID-PEROXIDATION; POTENTIAL ROLE; IN-VITRO; POLYPHENOLS; CELLS; INHIBITION; HISTOCHROME;
D O I：
10.1007/s11094-016-1450-x
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The role of the antioxidant properties of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone in the manifestation of its pharmacological effects is reviewed. Issues with pleiotropic cellular-molecular mechanisms of echinochrome A action are considered with emphasis on the unique antioxidant activity of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone. These properties in combination with a low destructive potential account for the prospects of expanding the therapeutic use of echinochrome A.
引用
收藏
页码：353 / 357
页数：5
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