Bcl2 flexible loop domain positively and negatively regulates survival function through direct interaction with p53.

被引：0
作者：
Deng, XM [1 ]
Gao, FQ [1 ]
Flagg, T [1 ]
Anderson, J [1 ]
May, WS [1 ]
机构：
[1] Univ Florida, UF Shands Canc Ctr, Gainesville, FL 32610 USA
来源：
BLOOD | 2005年 / 106卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2623
引用
收藏
页码：737A / 737A
页数：1
相关论文
共 50 条
  • [1] Bcl2's flexible loop domain regulates p53 binding and survival
    Deng, Xingming
    Gao, Fengqin
    Flagg, Tammy
    Anderson, Jessica
    May, W. Stratford
    MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (12) : 4421 - 4434
  • [2] Bcl2's Flexible Loop Domain Regulates p53 Binding and Survival (vol 26, pg 4421, 2006)
    Deng, Xingming
    Gao, Fengqin
    Flagg, Tammy
    Anderson, Jessica
    May, W. Stratford
    MOLECULAR AND CELLULAR BIOLOGY, 2020, 40 (21)
  • [3] Retinoblastoma binding protein 6 (RbBP6) gene in lung cancer:: Correlation with apoptosis, BCl2 and p53.
    Motadi, LL
    Dlamini, ZZ
    Bhoola, KK
    CLINICAL CANCER RESEARCH, 2005, 11 (24) : 9098S - 9098S
  • [4] Multiple-site Bcl2 phosphorylation in the flexible loop domain (FLD) unexpectedly enhances anti-apoptotic function.
    Deng, XM
    Gao, FQ
    Mai, HQ
    May, WS
    BLOOD, 2001, 98 (11) : 796A - 796A
  • [5] Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function
    Shen, Jia
    Sheng, Xiangpeng
    Chang, ZeNan
    Wu, Qian
    Wang, Sheng
    Xuan, Zongliang
    Li, Dan
    Wu, Yalan
    Shang, Yongjia
    Kong, Xiangtao
    Yu, Long
    Li, Lin
    Ruan, Kangchen
    Hu, Hongyu
    Huang, Ying
    Hui, Lijian
    Xie, Dong
    Wang, Fudi
    Hu, Ronggui
    CELL REPORTS, 2014, 7 (01): : 180 - 193
  • [6] Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice
    Jung, Cho-Rok
    Lim, Jung Hwa
    Choi, Yoonjung
    Kim, Dae-Ghon
    Kang, Koo Jeong
    Noh, Seung-Moo
    Im, Dong-Soo
    JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (12) : 4493 - 4506
  • [7] Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway
    Wang, Qinhong
    Gao, Fengqin
    May, W. Stratford
    Zhang, Yangde
    Zhang, Tammy
    Deng, Xingming
    MOLECULAR CELL, 2008, 29 (04) : 488 - 498
  • [8] Gelsolin negatively regulates the activity of tumor suppressor p53 through their physical interaction in hepatocarcinoma HepG2 cells
    An, Joo-Hee
    Kim, Jung-Woong
    Jang, Sang-Min
    Kim, Chul-Hong
    Kang, Eun-Jin
    Choi, Kyung-Hee
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 412 (01) : 44 - 49
  • [9] JNK2 Regulates Mammary Lineage Differentiation in Tumors and Normal Glands through Notch1 and p53.
    Cantrell, M. A.
    Ebelt, N. D.
    Van den, Berg C. L.
    CANCER RESEARCH, 2011, 71
  • [10] NOTCH1 intracellular domain negatively regulates PAK1 signaling pathway through direct interaction
    Yoon, Ji-Hye
    Mo, Jung-Soon
    Ann, Eun-Jung
    Ahn, Ji-Seon
    Jo, Eun-Hye
    Lee, Hye-Jin
    Hong, Se-Hoon
    Kim, Mi-Yeon
    Kim, Eung-Gook
    Lee, Keesook
    Park, Hee-Sae
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2016, 1863 (02): : 179 - 188
12345