Gold Nanoparticles: Promising Nanomaterials for the Diagnosis of Cancer and HIV/AIDS

被引：95
作者：
Kumar, Anil [1 ]
Boruah, Bhargavi Mazinder [2 ]
Liang, Xing-Jie [1 ]
机构：
[1] Chinese Acad Sci, Natl Ctr Nanosci & Nanotechnol, CAS Key Lab Biomed Effects Nanoparticles & Nanosa, Beijing 100190, Peoples R China
[2] Chinese Acad Sci, Inst Microbiol, CAS Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China
来源：
JOURNAL OF NANOMATERIALS | 2011年 / 2011卷
关键词：
SURFACE-PLASMON RESONANCE; POLY(BETA-AMINO ESTER) NANOPARTICLES; MOLECULARLY IMPRINTED POLYMER; ENHANCED RAMAN-SCATTERING; TUMOR-TARGETED DELIVERY; PH-SENSITIVE SYSTEM; OPTICAL-PROPERTIES; LUNG-CANCER; HYBRIDIZATION ADSORPTION; IMAGING MEASUREMENTS;
D O I：
10.1155/2011/202187
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Gold nanoparticles (AuNPs) are currently playing a significant role for human welfare in the field of clinical diagnosis as well as several biomedical applications. More and more research shows that AuNPs-based technologies are becoming promising approaches in cancer research and AIDS treatment. In this paper, we have focused mainly on the exploitation of unique and characteristic properties of AuNPs such as surface plasmon resonance (SPR), surface enhance Raman scattering (SERS), magnetic properties (MRI), and fluorescence behavior shown upon conjugation with biological and biocompatible ligands. These properties find wide prevalence in biodiagnostics like plasmon-based labeling and imaging, enzyme-linked immunosorbant assay (ELISA), and electrochemical-based methods that can pave the way for developing novel techniques towards diagnosis and therapy of cancer and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS).
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页数：17
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