Sexual Dysfunction Due to Psychotropic Medications

被引：45

作者：

Clayton, Anita H. ^{[1
]}

Alkis, Andrew R. ^{[1
]}

Parikh, Nishant B. ^{[1
]}

Votta, Jennifer G. ^{[1
]}

机构：

[1] Univ Virginia, Dept Psychiat & Neurobehav Sci, 1215 Lee St, Charlottesville, VA 22903 USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2016年 / 39卷 / 03期

关键词：

Sexual dysfunction; Antidepressant-induced sexual dysfunction; Antipsychotic-induced sexual dysfunction; Psychotropic-induced sexual dysfunction; Psychotropic adverse effects; MAJOR DEPRESSIVE DISORDER; SEROTONIN REUPTAKE INHIBITOR; PLACEBO-CONTROLLED TRIAL; RANDOMIZED CONTROLLED-TRIAL; FLUOXETINE-INDUCED ANORGASMIA; SUSTAINED-RELEASE BUPROPION; INDUCED RETROGRADE EJACULATION; SERUM PROLACTIN CONCENTRATIONS; TREATED SCHIZOPHRENIC-PATIENTS; DOUBLE-BLIND TRIAL;

D O I：

10.1016/j.psc.2016.04.006

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Sexual functioning is important to assess in patients with psychiatric illness as both the condition and associated treatment may contribute to sexual dysfunction (SD). Antidepressant medications, mood stabilizers, antipsychotics, and antianxiety agents may be associated with SD related to drug mechanism of action. Sexual adverse effects may be related to genetic risk factors, impact on neurotransmitters and hormones, and psychological elements. Effective strategies to manage medication-induced sexual dysfunction are initial choice of a drug unlikely to cause SD, switching to a different medication, and adding an antidote to reverse SD. Appropriate interventions should be determined on a clinical case-by-case basis.

引用

页码：427 / +

页数：38

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