Mycobacterium Avium Complex Septic Arthritis in a Patient Treated by Infliximab

被引：3

作者：

Chalhoub, Nathalie ^{[1
]}

Georgescu, Claudiu ^{[2
]}

Altorok, Nezam ^{[3
]}

机构：

[1] Univ Toledo, Med Ctr, Dept Internal Med, 2801 W Bancroft St, Toledo, OH 43606 USA

[2] Univ Toledo, Med Ctr, Dept Internal Med, Div Infect Dis, 2801 W Bancroft St, Toledo, OH 43606 USA

[3] Univ Toledo, Med Ctr, Dept Internal Med, Div Rheumatol & Immunol, 2801 W Bancroft St, Toledo, OH 43606 USA

来源：

AMERICAN JOURNAL OF THERAPEUTICS | 2016年 / 23卷 / 05期

关键词：

dermatomyositis; infliximab; mycobacterium avium complex; TUMOR-NECROSIS-FACTOR; MYCOPHENOLATE-MOFETIL; DERMATOMYOSITIS; TUBERCULOSIS; MICE;

D O I：

10.1097/MJT.0000000000000318

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Infliximab is one of the TNF- inhibitors, a class of medications that made a revolution in treatment of rheumatic diseases especially rheumatoid arthritis. The activation of tuberculosis and atypical mycobacterial infections has been described in the setting of TNF- inhibitor therapy, but septic arthritis relating to this treatment has not yet been reported in previous literature. We describe a 50-year-old woman with dermatomyositis who developed Mycobacterium Avium Complex septic arthritis, while being treated with infliximab for active skin disease. This case highlights an important complication related to therapy with TNF- inhibitors.

引用

页码：E1222 / E1225

页数：4

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