Non-Small-Cell Lung Cancer in 2022: A Review for General Practitioners in Oncology

被引:240
作者
Mithoowani, Hamid [1 ]
Febbraro, Michela [2 ]
机构
[1] Grand River Reg Canc Ctr, 835 King St W, Kitchener, ON N2G 1G3, Canada
[2] Hamilton Hlth Sci Ctr, Juravinski Canc Ctr, 699 Concess St, Hamilton, ON L8V 5C2, Canada
关键词
non-small cell lung cancer; lung cancer; screening; immunotherapy; iRAE; iRAEs; CAGPO; Canadian Association of General Practitioners in Oncology; ALK; EGFR; K-RAS; KRAS; OPEN-LABEL; SINGLE-ARM; CHEMOTHERAPY; OSIMERTINIB; CHEMORADIOTHERAPY; MULTICENTER; CRIZOTINIB; MUTATIONS; NIVOLUMAB; SELECTION;
D O I
10.3390/curroncol29030150
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Lung cancer is the leading cause of cancer death in Canada and a significant cause of morbidity for patients and their loved ones. There have been rapid advances in preventing, screening and treating this disease. Here, we present a contemporary review of treatment of non-small cell lung cancer in Canada based on current best practices. The focus of this review is to highlight recent data in screening for lung cancer, management of patients with early and locally-advanced non-small cell lung cancer, as well as management of patients with metastatic disease. There is a special focus on the incorporation of immunotherapy into practice and its associated toxicities.
引用
收藏
页码:1828 / 1839
页数:12
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