Two-photon probes for the endoplasmic reticulum: its detection in a live tissue by two-photon microscopy

被引:13
作者
Choi, Ji-Woo [1 ]
Choi, Seung-Hye [1 ]
Hong, Seung Taek [1 ]
Kim, Mun Seok [2 ]
Ryu, Seong Shick [1 ]
Yoon, Yeo Uk [2 ]
Paik, Kyu Cheol [2 ]
Han, Man So [2 ]
Sim, Taebo [1 ,3 ]
Cho, Bong Rae [1 ,2 ,4 ]
机构
[1] Korea Univ, KU KIST Grad Sch Converging Sci & Technol, 145 Anam Ro, Seoul 02841, South Korea
[2] Daejin Univ, Dept Chem, 1007 Hoguk Ro, Pocheon Si 11159, Gyeonggi Do, South Korea
[3] Yonsei Univ, Severance Biomed Sci Inst, Coll Med, 50 Yonsei Ro, Seoul 03722, South Korea
[4] Korea Univ, Dept Chem, 145 Anam Ro, Seoul 02841, South Korea
基金
新加坡国家研究基金会;
关键词
STRESS; MITOCHONDRIA; LYSOSOMES; DISEASE; CANCER; DEATH;
D O I
10.1039/d0cc00236d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report blue- and green-emitting two-photon probes derived from naphthalene and fluorene derivatives (as fluorophores) and an endoplasmic reticulum (ER) retrieval peptide (KDEL; as an ER-targeting moiety) that can detect the ER in a live cell by both one-photon and two-photon microscopy (TPM) and in a live tissue by TPM.
引用
收藏
页码:3657 / 3660
页数:4
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