Nimble progenitors rescue vascular grafts

被引:3
作者
Mooney, D [1 ]
机构
[1] Univ Michigan, Dept Biol & Mat Sci, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Chem Engn, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA
关键词
D O I
10.1038/nm0901-996b
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A new study shows that endothelial progenitor cells obtained from peripheral blood provide a suitable cell source for lining vascular grafts. This finding promises both short- and long-term medical advances in the cardiovascular and other medical arenas. (pages 1035–1040)
引用
收藏
页码:996 / 997
页数:2
相关论文
共 14 条
[1]   Isolation of putative progenitor endothelial cells for angiogenesis [J].
Asahara, T ;
Murohara, T ;
Sullivan, A ;
Silver, M ;
vanderZee, R ;
Li, T ;
Witzenbichler, B ;
Schatteman, G ;
Isner, JM .
SCIENCE, 1997, 275 (5302) :964-967
[2]   VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells [J].
Asahara, T ;
Takahashi, T ;
Masuda, H ;
Kalka, C ;
Chen, DH ;
Iwaguro, H ;
Inai, Y ;
Silver, M ;
Isner, JM .
EMBO JOURNAL, 1999, 18 (14) :3964-3972
[3]   From marrow to brain: Expression of neuronal phenotypes in adult mice [J].
Brazelton, TR ;
Rossi, FMV ;
Keshet, GI ;
Blau, HM .
SCIENCE, 2000, 290 (5497) :1775-1779
[4]   Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization [J].
Kalka, C ;
Masuda, H ;
Takahashi, T ;
Kalka-Moll, WM ;
Silver, M ;
Kearney, M ;
Li, T ;
Isner, JM ;
Asahara, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (07) :3422-3427
[5]   Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo [J].
Kaushal, S ;
Amiel, GE ;
Guleserian, KJ ;
Shapira, OM ;
Perry, T ;
Sutherland, FW ;
Rabkin, E ;
Moran, AM ;
Schoen, FJ ;
Atala, A ;
Soker, S ;
Bischoff, J ;
Mayer, JE .
NATURE MEDICINE, 2001, 7 (09) :1035-1040
[6]   Development of biocompatible synthetic extracellular matrices for tissue engineering [J].
Kim, BS ;
Mooney, DJ .
TRENDS IN BIOTECHNOLOGY, 1998, 16 (05) :224-230
[7]   A completely biological tissue-engineered human blood vessel [J].
L'Heureux, N ;
Pâquet, S ;
Labbé, R ;
Germain, L ;
Auger, FA .
FASEB JOURNAL, 1998, 12 (01) :47-56
[8]   Purified hematopoietic stem cells can differentiate into hepatocytes in vivo [J].
Lagasse, E ;
Connors, H ;
Al-Dhalimy, M ;
Reitsma, M ;
Dohse, M ;
Osborne, L ;
Wang, X ;
Finegold, M ;
Weissman, IL ;
Grompe, M .
NATURE MEDICINE, 2000, 6 (11) :1229-1234
[9]   Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep [J].
Liechty, KW ;
MacKenzie, TC ;
Shaaban, AF ;
Radu, A ;
Moseley, AB ;
Deans, R ;
Marshak, DR ;
Flake, AW .
NATURE MEDICINE, 2000, 6 (11) :1282-1286
[10]  
Meinhart J, 1997, ASAIO J, V43, pM515