Boc2O mediated macrolactonisation:: Formal chemoenzymatic synthesis of macrolide antibiotic (-) A26771B

被引：15

作者：

Nagarajan, M ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 06期

关键词：

macrolides; hydroxylation; enzyme reactions; lactonisation;

D O I：

10.1016/S0040-4039(98)02567-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient stereocontrolled, formal chemoenzymatic synthesis of macrolide antibiotic A26771B (1) using the improved macrolactonisation reagent, Boc(2)O-iPr(2) NEt/pyrrolidinopyridine(4-PP) is reported (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：1207 / 1210

页数：4

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