Boc2O mediated macrolactonisation:: Formal chemoenzymatic synthesis of macrolide antibiotic (-) A26771B

被引：15
|
作者：
Nagarajan, M [1 ]
机构：
[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 06期
关键词：
macrolides; hydroxylation; enzyme reactions; lactonisation;
D O I：
10.1016/S0040-4039(98)02567-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient stereocontrolled, formal chemoenzymatic synthesis of macrolide antibiotic A26771B (1) using the improved macrolactonisation reagent, Boc(2)O-iPr(2) NEt/pyrrolidinopyridine(4-PP) is reported (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1207 / 1210
页数：4
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