Congenital toxoplasmosis - Specific IgG subclasses in mother/newborn pairs

被引：18

作者：

Canedo-Solares, Irma ^{[1
]}

Galvan-Ramirez, Maria de la Luz ^{[2
]}

Luna-Pasten, Hector ^{[1
]}

Perez, Laura Rocio Rodriguez ^{[2
]}

Ortiz-Alegria, Luz Belinda ^{[1
]}

Rico-Torres, Claudia Patricia ^{[1
]}

Vela-Antieva, Marcela ^{[1
]}

Perez-Andrade, Martha ^{[1
]}

Figueroa-Damian, Ricardo ^{[3
]}

Correa, Dolores ^{[1
]}

机构：

[1] Inst Nacl Pediat, Subdirecc Med Expt, Lab Immunol Expt, Mexico City, DF, Mexico

[2] Univ Guadalajara, Ctr Univ Ciencias Salud, Guadalajara, Spain

[3] Inst Nacl Perinatol, Secretaria Salud, Mexico City, DF, Mexico

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2008年 / 27卷 / 05期

关键词：

antibodies; congenital toxoplasmosis; fetal response; IgG subclasses; placenta;

D O I：

10.1097/INF.0b013e31816591df

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Anti-Toxoplasma gondii antibodies of all IgG subclasses were studied in mother/newborn pairs. IgG1 in the mothers and IgG3 in the newborns were related to offspring clinical problems; IgG2 and IgG3 in the babies were markers of vertical transmission, and IgG4 in mothers or children were associated to clinical problems. IgG subclasses may be markers of congenital infection or clinical outcome.

引用

页码：469 / 474

页数：6

共 12 条

[1]

[Anonymous], 2000, Congenital toxoplasmosis : scientific background, clinical management, and control

[2]

Ee T Y, 1989, Southeast Asian J Trop Med Public Health, V20, P71

[3] INDIRECT FLUORESCENT ANTIBODY TECHNIQUE IN SEROLOGY OF TOXOPLASMA GONDII [J].

FLETCHER, S .

JOURNAL OF CLINICAL PATHOLOGY, 1965, 18 (02) :193-&

[4] TOXOPLASMA ANTIGENS RECOGNIZED BY IMMUNOGLOBULIN-G SUBCLASSES DURING ACUTE AND CHRONIC INFECTION [J].

HUSKINSON, J ;

STEPICKBIEK, PN ;

ARAUJO, FG ;

THULLIEZ, P ;

SUZUKI, Y ;

REMINGTON, JS .

JOURNAL OF CLINICAL MICROBIOLOGY, 1989, 27 (09) :2031-2038

[5] Role of interleukin-2 and interferon-gamma in inducing production of IgG subclasses in lymphocytes of human newborns [J].

Kawano, Y ;

Noma, T .

IMMUNOLOGY, 1996, 88 (01) :40-48

[6] Acute and chronic phases of Toxoplasma gondii infection in mice modulate the host immune responses [J].

Nguyen, TD ;

Bigaignon, G ;

Van Broeck, J ;

Vercammen, M ;

Nguyen, TN ;

Delmee, M ;

Turneer, M ;

Wolf, SF ;

Coutelier, JP .

INFECTION AND IMMUNITY, 1998, 66 (06) :2991-2995

[7] Fc receptors and immunity to parasites [J].

Pleass, RJ ;

Woof, JM .

TRENDS IN PARASITOLOGY, 2001, 17 (11) :545-551

[8] DYES AS MICROCHEMICAL INDICATORS OF A NEW IMMUNITY PHENOMENON AFFECTING A PROTOZOON PARASITE (TOXOPLASMA) [J].

SABIN, AB ;

FELDMAN, HA .

SCIENCE, 1948, 108 (2815) :660-663

[9] Toxoplasma gondii infection in pregnancy:: opportunities and pitfalls of serological diagnosis [J].

Sensini, A .

CLINICAL MICROBIOLOGY AND INFECTION, 2006, 12 (06) :504-512

[10] Placental transport of immunoglobulin G [J].

Simister, NE .

VACCINE, 2003, 21 (24) :3365-3369

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