Uterine sarcomas

被引：9

作者：

Pautier, P. ^{[1
]}

机构：

[1] Inst Gustave Roussy, Comite Gynecol, F-94805 Villejuif, France

来源：

ONCOLOGIE | 2007年 / 9卷 / 02期

关键词：

sarcoma; uterine tumor; leiomyosarcoma; mixte mesodermal tumor; endometrial sarcoma;

D O I：

10.1007/s10269-006-0545-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Uterine sarcomas (US) are rare tumors representing less than 5 % of uterine malignancies. They carry a poor prognosis characterized by a high rate of local and metastatic recurrences. Surgical treatment consists in hysterectomy and bilateral oophorectomy; pelvic lymphnode dissection is recommended in carcinosarcomas only. Despite the high risks of metastatic evolution, few prospective randomised studies have been conduct in an adjuvant setting. Pelvic radiotherapy after surgery is recommended to enhance local control. The only phase III of adjuvant chemotherapy is negative but difficult to interpret. A French study is actually ongoing studying the effects of adjuvant polychemotherapy (adriamycin, cisplatin and ifosfamide).

引用

页码：137 / 143

页数：7

共 58 条

[1] Uterine carcinosarcomas: Incidence and trends in management and survival [J].

Arrastia, CD ;

Fruchter, RG ;

Clark, M ;

Maiman, M ;

Remy, JC ;

Macasaet, M ;

Gates, EJ ;

DiMaio, T ;

Marzec, T .

GYNECOLOGIC ONCOLOGY, 1997, 65 (01) :158-163

[2]

BERCHUCK A, 1988, OBSTET GYNECOL, V71, P845

[3] THE SIGNIFICANCE OF EPITHELIAL DIFFERENTIATION IN MIXED MESODERMAL TUMORS OF THE UTERUS - A CLINICOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY [J].

BITTERMAN, P ;

CHUN, B ;

KURMAN, RJ .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1990, 14 (04) :317-328

[4] Paclitaxel in the treatment of carcinosarcoma of the uterus: A gynecologic oncology group study [J].

Curtin, JP ;

Blessing, JA ;

Soper, JT ;

DeGeest, K .

GYNECOLOGIC ONCOLOGY, 2001, 83 (02) :268-270

[5] Tamoxifen-related uterine malignancies: carcinomas or sarcomas? [J].

Delaloge, S ;

Pautier, P ;

Duvillard, P .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2004, 14 (02) :395-395

[6] Impact of radiotherapy on local control and survival in uterine sarcomas:: A retrospective study from the Grup Oncologic Catala-Occita [J].

Ferrer, F ;

Sabater, S ;

Farrús, B ;

Guedea, F ;

Rovirosa, A ;

Anglada, L ;

Delannes, M ;

Marín, S ;

DuBois, JB ;

Daly-Schveitzer, N .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1999, 44 (01) :47-52

[7] UTERINE SARCOMAS - PROGNOSTIC FACTORS AND TREATMENT MODALITIES - STUDY ON 209 PATIENTS [J].

GEORGE, M ;

PEJOVIC, MH ;

KRAMAR, A .

GYNECOLOGIC ONCOLOGY, 1986, 24 (01) :58-67

[8]

HARLOW BL, 1986, J NATL CANCER I, V76, P399

[9] Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: Results of a phase II trial [J].

Hensley, ML ;

Maki, R ;

Venkatraman, E ;

Geller, G ;

Lovegren, M ;

Aghajanian, C ;

Sabbatini, P ;

Tong, W ;

Barakat, R ;

Spriggs, DR .

JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (12) :2824-2831

[10]

Jones G.W., 1991, CLIN INVEST MED S19, V14, pA772

← 1 2 3 4 5 6 →