The circadian clock regulates metabolic responses to physical exercise

被引：4

作者：

Cheng, Qianyun ^{[1
]}

Lu, Chao ^{[1
]}

Qian, Ruizhe ^{[1
]}

机构：

[1] Fudan Univ, Sch Basic Med Sci, Dept Physiol & Pathophysiol, Shanghai 200032, Peoples R China

来源：

CHRONOBIOLOGY INTERNATIONAL | 2022年 / 39卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Circadian clock; skeletal muscle metabolism; physical exercise; metabolic syndrome; aging; MUSCLE INSULIN SENSITIVITY; FIBER-TYPE TRANSFORMATION; SKELETAL-MUSCLE; MITOCHONDRIAL BIOGENESIS; GLUCOSE-METABOLISM; ENDOCRINE ORGAN; PERFORMANCE; PHYSIOLOGY; ENDURANCE; RHYTHMS;

D O I：

10.1080/07420528.2022.2050384

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

It has been proposed for years that physical exercise ameliorates metabolic diseases. Optimal exercise timing in humans and mammals has indicated that circadian clocks play a vital role in exercise and body metabolism. Skeletal muscle metabolism exhibits a robust circadian rhythm under the control of the suprachiasmatic nucleus of the hypothalamus. Clock genes also control the development, differentiation, and function of skeletal muscles. In this review, we aimed to clarify the relationship between exercise, skeletal muscles, and the circadian clock. Health benefits can be attained by the scheduling of exercise at the best circadian time. Exercise therapy for metabolic diseases and cardiovascular health is a key adjuvant method. This review highlights the importance of exercise timing in maintaining healthy metabolism and circadian clocks.

引用

页码：907 / 917

页数：11

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