Clinical Observations on the Dose-effect Relationship of Gegen Qin Lian Decoction (sic) on 54 Out-patients with Type 2 Diabetes

被引：48

作者：

Tong Xiao-lin ^{[1
]}

Zhao Lin-hua ^{[1
]}

Lian Feng-mei ^{[1
]}

Zhou Qiang ^{[1
]}

Xia Le ^{[2
]}

Zhang Jia-cheng ^{[2
]}

Chen Xin-yan ^{[2
]}

Ji Hang-yu ^{[2
]}

机构：

[1] China Acad Chinese Med Sci, Guang Anmen Hosp, Beijing 100053, Peoples R China

[2] Beijing Univ Chinese Med, Beijing 100029, Peoples R China

来源：

JOURNAL OF TRADITIONAL CHINESE MEDICINE | 2011年 / 31卷 / 01期

关键词：

Gegen Qin Lian Decoction; dose-effect relationship; type2; diabetes;

D O I：

10.1016/S0254-6272(11)60013-7

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Objective: To observe the therapeutic effect of different dosages of Gegen Qin Lian Decoction (sic) on type 2 diabetic patients. Methods: Fifty-four type 2 diabetic patients from low dosage group (20 cases), medium dosage group (19 cases) and high dosage group (15 cases) were treated with different dosage of Gegen Qin Lian Decoction for 12 weeks. Fasting blood-glucose (FBG), postprandial blood sugar (PBG) and Hemoglobin Alc (HbAlc) were determined before and after treatment. Results: With the increase of dosage, the overall effective rate of glycaemic control increased, and FBG, PBG, HbAlc decreased. The overall effective rate of blood glucose control of high dosage, medium dosage and low dosage group were 80%, 47%, 30% respectively, and there were significant differences between high dosage group and low dosage group. The decrease of FBG, PBG and HbAlc of high dosage showed significant differences from low dosage too. These data was analyzed by trend chi(2) test and covariance analysis. Conclusion: The result indicated that different dosage of Gegen Qin Lian Decoction has dose-effect relationship in reducing HbAlc and FBG.

引用

页码：56 / 59

页数：4

共 8 条

[1]

[Anonymous], 2002, Guiding principles for clinical research of new Traditional Chinese Medicines

[2]

DING XP, 2004, COMBINATION TCM W ME, P42

[3]

Ke X.F., 1983, SHANGHAI J TCM, V12, P36

[4]

Li SZ, 2002, COMPENDIUM MAT MED, P41

[5]

WANG YM, 1986, J BEIJING TCM COLL, V2, P10

[6]

XIONG MQ, 2003, FEBRILE DIS, P439

[7]

Zeng Yi-peng, 2006, Zhongguo Zhong Xi Yi Jie He Za Zhi, V26, P514

[8]

ZHU S, 1956, J TCM, V10, P531

← 1 →