The eukaryotic genome as an RNA machine

被引：469

作者：

Amaral, Paulo P. ^{[1
]}

Dinger, Marcel E. ^{[1
]}

Mercer, Tim R. ^{[1
]}

Mattick, John S. ^{[1
]}

机构：

[1] Univ Queensland, Inst Mol Biosci, St Lucia, Qld 4072, Australia

来源：

SCIENCE | 2008年 / 319卷 / 5871期

关键词：

D O I：

10.1126/science.1155472

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The past few years have revealed that the genomes of all studied eukaryotes are almost entirely transcribed, generating an enormous number of non-protein-coding RNAs (ncRNAs). In parallel, it is increasingly evident that many of these RNAs have regulatory functions. Here, we highlight recent advances that illustrate the diversity of ncRNA control of genome dynamics, cell biology, and developmental programming.

引用

页码：1787 / 1789

页数：3

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