Template-Free Synthesis of Mesoporous Polymers for Highly Selective Enrichment of Glycopeptides

被引：46
作者：
Jin, Tian [1 ,2 ]
Xiong, Zhichao [1 ,2 ,5 ]
Zhu, Xiang [1 ,2 ,3 ]
Mehio, Nada [4 ]
Chen, Yajing [1 ,2 ]
Hu, Jun [1 ,2 ]
Zhang, Weibing [1 ,2 ]
Zou, Hanfa [5 ]
Liu, Honglai [1 ,2 ]
Dai, Sheng [4 ]
机构：
[1] E China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China
[2] E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China
[3] Tech Univ Dresden, Dept Chem & Food Chem, D-01062 Dresden, Germany
[4] Oak Ridge Natl Lab, Div Chem Sci, Oak Ridge, TN 37831 USA
[5] Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China
来源：
ACS MACRO LETTERS | 2015年 / 4卷 / 05期
基金：
中国国家自然科学基金;
关键词：
MAGNETIC NANOPARTICLES; PERFORMANCE;
D O I：
10.1021/acsmacrolett.5b00235
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
A facile template-free strategy for the synthesis of mesoporous phenolic polymers with attractive porosities, nitrogen-containing functionalities, and intrinsic hydrophilic skeletons is presented. The resultant polymer has a high BET surface area (548 m(2) g(-1)) and mesopore size (13 nm) and exhibits superior glycopeptide-capturing performance, thus, revealing the potential application of mesoporous polymers in highly selective glycopeptide enrichment. This general capture protocol may open up new opportunities for the development of glycoproteomes.
引用
收藏
页码：570 / 574
页数：5
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