Evaluating a web- and telephone-based personalised exercise intervention for individuals living with metastatic prostate cancer (ExerciseGuide): protocol for a pilot randomised controlled trial

被引：12

作者：

Evans, Holly E. L. ^{[1
]}

Forbes, Cynthia C. ^{[2
]}

Galvao, Daniel A. ^{[3
]}

Vandelanotte, Corneel ^{[4
]}

Newton, Robert U. ^{[3
,5
]}

Wittert, Gary ^{[1
]}

Chambers, Suzanne ^{[6
]}

Vincent, Andrew D. ^{[1
]}

Kichenadasse, Ganessan ^{[7
]}

Brook, Nicholas ^{[8
]}

Girard, Danielle ^{[9
]}

Short, Camille E. ^{[1
,10
]}

机构：

[1] Univ Adelaide, Freemasons Fdn Ctr Mens Hlth, Sch Med, Adelaide, SA, Australia

[2] Univ Hull, Wolfson Palliat Care Res Ctr, Inst Clin & Appl Hlth Res, Kingston Upon Hull, N Humberside, England

[3] Edith Cowan Univ, Exercise Med Res Inst, Joondalup, WA, Australia

[4] Cent Queensland Univ, Sch Hlth Med & Appl Sci, Appleton Inst, Phys Act Res Grp, North Rockhampton, Qld, Australia

[5] Univ Queensland, Sch Human Movement & Nutr Sci, Brisbane, Qld, Australia

[6] Univ Technol, Fac Hlth, Sydney, NSW, Australia

[7] Flinders Ctr Innovat Canc, Coll Med & Publ Hlth, Bedford Pk, SA, Australia

[8] Univ Adelaide, Sch Med, Dept Surg, Adelaide, SA, Australia

[9] Univ South Australia, Allied Hlth & Human Performance, Alliance Res Exercise Nutr & Act, Adelaide, SA, Australia

[10] Univ Melbourne, Fac Med Dent & Hlth Sci, Melbourne Ctr Behav Change, Parkville, Vic, Australia

来源：

PILOT AND FEASIBILITY STUDIES | 2021年 / 7卷 / 01期

基金：

英国医学研究理事会;

关键词：

Exercise; Metastatic prostate cancer; Behavioural change; eHealth; Computer tailoring; Aerobic; Resistance training; QUALITY-OF-LIFE; BEHAVIOR-CHANGE INTERVENTIONS; SOCIAL COGNITIVE THEORY; PHYSICAL-ACTIVITY; RESISTANCE EXERCISE; BONE METASTASES; METAANALYSIS; SURVIVORS; MEN; QUESTIONNAIRE;

D O I：

10.1186/s40814-020-00763-2

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Introduction: Preliminary research has shown the effectiveness of supervised exercise-based interventions in alleviating sequela resulting from metastatic prostate cancer. Despite this, many individuals do not engage in sufficient exercise to gain the benefits. There are many barriers, which limit the uptake of face-to-face exercise in this population including lack of suitable facilities, remoteness, and access to experts, significant fatigue, urinary incontinence and motivation. Technology-enabled interventions offer a distance-based alternative. This protocol describes a pilot two-armed randomised controlled study that will investigate the feasibility and preliminary efficacy of an online exercise and behavioural change tool (ExerciseGuide) amongst individuals with metastatic prostate cancer. Methods: Sixty-six participants with histologically diagnosed metastatic prostate cancer will be randomised into either the 8-week intervention or a wait-list control. The intervention arm will have access to a tailored website, remote supervision, and tele-coaching sessions to enhance support and adherence. Algorithms will individually prescribe resistance and aerobic exercise based upon factors such as metastasis location, pain, fatigue, confidence and current exercise levels. Behavioural change strategies and education on exercise benefits, safety and lifestyle are also tailored through the website. The primary outcome will be intervention feasibility (safety, usability, acceptability, and adherence). Secondary exploratory outcomes include changes in physical activity, quality of life, sleep, and physical function. Outcomes will be measured at baseline and week 9. Discussion: The study aims to determine the potential feasibility of an online remotely monitored exercise intervention developed for individuals with metastatic prostate cancer. If feasible, this pilot intervention will inform the design and implementation of further distance-based interventions.

引用

页数：16

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