Assessment of atrial conduction time in patients with essential hypertension

被引:42
作者
Emiroglu, Mehmet Yunus [1 ]
Bulut, Mustafa [1 ]
Sahin, Muslim [1 ]
Acar, Gurkan [2 ]
Akcakoyun, Mustafa [1 ]
Kargin, Ramazan [1 ]
Kayancicek, Hidayet [3 ]
Karapinar, Hekim [3 ]
Aung, Soe Moe [1 ]
机构
[1] Kartal Kosuyolu Cardiovasc Res & Training Hosp, Dept Cardiol, Istanbul, Turkey
[2] Kahramanmaras Sutcu Imam Univ, Dept Cardiol, Kahramanmaras, Turkey
[3] Van Cardiovasc Res & Training Hosp, Dept Cardiol, Van, Turkey
关键词
Hypertension; Tissue Doppler imaging; Atrial electromechanical delay; Intra and inter atrial conduction time; P wave dispersion; Electrophysiological study; P-WAVE DISPERSION; VENTRICULAR DIASTOLIC FUNCTION; HEART-RATE-VARIABILITY; COLLAGEN TYPE-I; MYOCARDIAL FIBROSIS; SAMPLING FREQUENCY; FIBRILLATION; DURATION; ECHOCARDIOGRAPHY; HEMODIALYSIS;
D O I
10.1016/j.jelectrocard.2010.09.012
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: We aimed to assess atrial conduction time in patients with essential hypertension. Methods: A total of 80 patients with hypertension (51 males/29 females, 53 +/- 12.5 years) and 80 controls (50 males/30 females, 50 +/- 12 years) were included. Atrial electromechanical coupling (time interval from the onset of P wave on surface electrocardiogram [ECG] to the beginning of A wave interval with tissue Doppler echocardiography [PA]), intraatrial and interatrial electromechanical delay (intra and inter atrial electromechanical delay [AEMD]), and P-wave dispersion (Pd) were measured (Appelton, C.P., Hatle, L., Popp, R.L., Relation of transmitral flow velocity patterns to left ventricular diastolic function: new insights from combined hemodynamic and Doppler echocardiographic study. J Am Coll Cardiol. 1988; 12: 426-440). Results: Atrial electromechanical coupling at the left lateral mitral annulus (PA lateral) and septal mitral annulus were longer in patients with hypertension (63.0 +/- 8.0 vs 50.2 +/- 4.3, P < .001, and 53.3 +/- 6.2 vs 40.1 +/- 5.5, P < .001). Interatrial (PA lateral-PA tricuspid) and intraatrial electromechanical delay (PA septum-PA tricuspid) were longer in patients with hypertension (24.8 +/- 7.2 vs 12.4 +/- 4.3, P < .001, and 14.1 +/- 4.5 vs 2.3 +/- 1.6, P < .001, respectively). Maximum P-wave duration and Pd were higher in patients with hypertension compared with controls (95.6 +/- 8.0 vs 90.1 +/- 9.5, P = .01, and 41.3 +/- 7.1 vs 33.5 +/- 6.1 P < .001, respectively). In correlation analysis, a positive correlation was detected between interatrial electromechanical delay and Pd (r = 0.72, P < .001). There was a moderate correlation between left ventricular mass index and PA lateral (r = 0.48, P < .001). Conclusion: Our results revealed that interatrial electromechanical delay and Pd were prolonged in patients with hypertension. Our results also showed a correlation between interatrial electromechanical delay and Pd. Prolonged electromechanical delay and Pd found in hypertensive patients could be related with increased incidence of atrial fibrillation in these patients. Prospective studies are needed to document the association between intraatrial and interatrial electromechanical delays and the development of atrial fibrillation. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:251 / 256
页数:6
相关论文
共 38 条
[1]  
[Anonymous], 2001, CIRCULATION, V104, P2118
[2]   P wave dispersion on 12-lead electrocardiography in patients with paroxysmal atrial fibrillation [J].
Aytemir, K ;
Özer, N ;
Atalar, E ;
Sade, E ;
Aksöyek, S ;
Övünç, K ;
Oto, A ;
Özmen, F ;
Kes, S .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2000, 23 (07) :1109-1112
[3]   Predictors of Atrial Fibrillation Recurrence After Radiofrequency Catheter Ablation: A Systematic Review [J].
Balk, Ethan M. ;
Garlitski, Ann C. ;
Alsheikh-Ali, Alawi A. ;
Terasawa, Teruhiko ;
Chung, Mei ;
Ip, Stanley .
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2010, 21 (11) :1208-1216
[4]  
Beinart R, 2010, J CARDIOVASC ELECTRO
[5]   Assessment of atrial conduction in patients with scleroderma by tissue Doppler Echocardiography and p wave dispersion [J].
Can, Ilknur ;
Onat, Ahmet Mesut ;
Aytemir, Kudret ;
Akdogan, Ali ;
Ureten, Kemal ;
Kiraz, Sedat ;
Ertenli, Ihsan ;
Ozer, Necla ;
Tokgozoglu, Lale ;
Oto, Ali .
CARDIOLOGY, 2007, 108 (04) :317-321
[6]   Assessment of atrial electromechanical coupling and influential factors in nonrheumatic paroxysmal atrial fibrillation [J].
Cui, Qi-Qiong ;
Zhang, Wei ;
Wang, Hu ;
Sun, Xin ;
Wang, Rong ;
Yang, Huan-Yi ;
Meng, Xian-Qiang ;
Zhang, Yun ;
Wang, Hao .
CLINICAL CARDIOLOGY, 2008, 31 (02) :74-78
[7]   Systolic and diastolic time intervals measured from Doppler tissue imaging: Normal values and Z-score tables, and effects of age, heart rate, and body surface area [J].
Cui, Wei ;
Roberson, David A. ;
Chen, Zhen ;
Madronero, Luisa F. ;
Cuneo, Bettina F. .
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2008, 21 (04) :361-370
[8]   Intra- and interatrial conduction delay: Implications for cardiac pacing [J].
Daubert, JC ;
Pavin, D ;
Jauvert, G ;
Mabo, P .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2004, 27 (04) :507-525
[9]   Clinical aspects of hypertensive myocardial fibrosis [J].
Díez, J ;
López, B ;
Gonzádlez, A ;
Querejeta, R .
CURRENT OPINION IN CARDIOLOGY, 2001, 16 (06) :328-335
[10]   Clinical and electrocardiographic predictors of recurrent atrial fibrillation [J].
Dilaveris, PE ;
Gialafos, EJ ;
Andrikopoulos, GK ;
Richter, DJ ;
Papanikolaou, V ;
Poralis, K ;
Gialafos, JE .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2000, 23 (03) :352-358