The Christmas season as a risk factor for chronic obstructive pulmonary disease exacerbations

被引:13
|
作者
Johnston, Neil W. [1 ]
McIvor, Andrew [1 ]
Lambert, Kim [1 ]
Greene, Justina M. [1 ]
Hussack, Pat [1 ]
de Verdier, Maria Gerhardsson [2 ]
Higenbottam, Tim [3 ]
Lewis, Jonathan [3 ]
Newbold, Paul [3 ]
Herath, Athula [4 ]
Jenkins, Martin [4 ]
机构
[1] McMaster Univ, Firestone Inst Resp Hlth, Hamilton, ON L8N 4A6, Canada
[2] AstraZeneca, Resp & Inflammat Therapy Area, Lund, Sweden
[3] AstraZeneca Charnwood, Resp & Inflammat Therapy Area, Loughborough, Leics, England
[4] AstraZeneca, Biostat, Macclesfield, Cheshire, England
关键词
Christmas; COPD; Epidemiology; Respiratory viruses; RESPIRATORY VIRUSES; HOSPITAL ADMISSIONS; COPD EXACERBATIONS; UNITED-STATES; ASTHMA; INFLUENZA; INFECTIONS; PNEUMONIA; EPIDEMIC; SCHOOL;
D O I
10.1155/2010/460532
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
BACKGROUND: Epidemics of hospitalization for chronic obstructive pulmonary disease (COPD) occur annually during the Christmas holidays, and COPD exacerbations commonly coincide with respiratory viral infections. OBJECTIVE: To compare the incidence and determinants of COPD exacerbations occurring between the Christmas holiday period and the remainder of the winter season. METHODS: Seventy-one subjects with COPD of mixed severity faxed daily symptom diaries to a computer monitoring system from December 1, 2006, to April 30, 2007. Possible exacerbations prompted a home visit for assessment, spirometry and specimen collection for virological testing. RESULTS: Study subjects submitted a total of 95.4% of possible daily symptom diary sheets by fax. Of 114 possible COPD exacerbations detected using the faxed diaries, 110 met the Anthonisen criteria for true exacerbations. A total of 47 exacerbations (mean 6.7/week) occurred during the Christmas holiday period, while 63 exacerbations (mean 4.3/week) occurred during the remainder of winter. Of the Christmas period exacerbations and of those in the balance of winter, 21 (44%) and 20 (32%), respectively, coincided with respiratory viral infections. CONCLUSIONS: The incidence of COPD exacerbations during the Christmas period was greater than during the rest of winter in 2006/2007 and peaked immediately before Christmas - in contrast to hospital presentation for COPD, which peaked during the Christmas week. No clear role of respiratory viral infections in the increased rate of exacerbations during the Christmas period was established in the present study. COPD patients were highly compliant with daily symptom reporting using faxed daily diaries, which permitted nearly complete detection of all exacerbations that occurred at incidence.
引用
收藏
页码:275 / 281
页数:7
相关论文
共 50 条
  • [21] Predictors of chronic obstructive pulmonary disease exacerbations
    Ishii, Takeo
    Kida, Kozui
    CURRENT OPINION IN PULMONARY MEDICINE, 2014, 20 (02) : 138 - 145
  • [22] Oxidative Stress Biomarkers in Chronic Obstructive Pulmonary Disease Exacerbations: A Systematic Review
    Zinellu, Elisabetta
    Zinellu, Angelo
    Fois, Alessandro G.
    Pau, Maria Carmina
    Scano, Valentina
    Piras, Barbara
    Carru, Ciriaco
    Pirina, Pietro
    ANTIOXIDANTS, 2021, 10 (05)
  • [23] Bacterial infection in acute exacerbations of chronic obstructive pulmonary disease
    Ben Abdallah, Fatma Chermiti
    Bouhawel, Wafa
    Sahnoun, Imen
    Mahouachi, Ridha
    Chtourou, Amel
    Taktak, Sofia
    Ben Kheder, Ali
    EUROPEAN RESPIRATORY JOURNAL, 2012, 40
  • [24] Determinants of bacteriological outcomes in exacerbations of chronic obstructive pulmonary disease
    Sethi, S.
    Anzueto, A.
    Miravitlles, M.
    Arvis, P.
    Alder, J.
    Haverstock, D.
    Trajanovic, M.
    Wilson, R.
    INFECTION, 2016, 44 (01) : 65 - 76
  • [25] β-Blocker Use and Incidence of Chronic Obstructive Pulmonary Disease Exacerbations
    Farland, Michelle Z.
    Peters, Cassey J.
    Williams, Juli D.
    Bielak, Kenneth M.
    Heidel, R. Eric
    Ray, Shaunta' M.
    ANNALS OF PHARMACOTHERAPY, 2013, 47 (05) : 651 - 656
  • [26] Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease
    Ni, Han
    Aye, Swe Zin
    Naing, Cho
    COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2022, (05):
  • [27] Unmet needs in the management of exacerbations of chronic obstructive pulmonary disease
    Waeijen-Smit, Kiki
    Houben-Wilke, Sarah
    DiGiandomenico, Antonio
    Gehrmann, Ulf
    Franssen, Frits M. E.
    INTERNAL AND EMERGENCY MEDICINE, 2021, 16 (03) : 559 - 569
  • [28] Management of chronic obstructive pulmonary disease: A review focusing on exacerbations
    Bollmeier, Suzanne G.
    Hartmann, Aaron P.
    AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2020, 77 (04) : 259 - 268
  • [29] Viral infections in exacerbations of asthma and chronic obstructive pulmonary disease
    Contoli, M.
    Marku, B.
    Conti, V.
    Saturni, S.
    Caramori, G.
    Papi, A.
    MINERVA MEDICA, 2009, 100 (06) : 467 - 478
  • [30] Phenotypes, Etiotypes, and Endotypes of Exacerbations of Chronic Obstructive Pulmonary Disease
    Bhatt, Surya P.
    Agusti, Alvar
    Bafadhel, Mona
    Christenson, Stephanie A.
    Bon, Jessica
    Donaldson, Gavin C.
    Sin, Don D.
    Wedzicha, Jadwiga A.
    Martinez, Fernando J.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 208 (10) : 1026 - 1041