Synthesis of covalently linked parallel and antiparallel DNA duplexes containing the metal-mediated base pairs T-Hg(II)-T and C-Ag(I)-C

被引：32

作者：

Ono, Takashi ^{[1
]}

Yoshida, Kyohei ^{[1
]}

Saotome, Yuko ^{[1
]}

Sakabe, Rei ^{[1
]}

Okamoto, Itaru ^{[1
]}

Ono, Akira ^{[1
]}

机构：

[1] Kanagawa Univ, Fac Engn, Dept Mat & Life Chem, Kanagawa Ku, Kanagawa 2218686, Japan

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 05期

关键词：

INTERSTRAND CROSS-LINK; HG-II; OLIGODEOXYNUCLEOTIDE; OLIGONUCLEOTIDES; REPAIR; MOTIF; IONS; NMR;

D O I：

10.1039/c0cc02028a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

DNA duplexes fixed in anti-parallel and parallel orientations by introducing covalent linkages have been synthesized and metal ions, Hg(II) and Ag(I), were incorporated into pyrimidine-pyrimidine base pairs.

引用

页码：1542 / 1544

页数：3

共 3 条

[1] Crystal structure of metallo-DNA duplex containing T-Hg(II)-T base pairs
Kondo, J.
Yamada, T.
Hirose, C.
Okamoto, I.
Tanaka, Y.
Ono, A.
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2014, 70 : C1375 - C1375
[2] DNA strands complementary in parallel orientation, form an antiparallel duplex at neutral pH with A-C, G-T and T-C mismatched base pairs.
Chary, KVR
Bhaumik, SR
Govil, G
Liu, K
Miles, HT
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 1996, 65 : PB123 - PB123
[3] Mesoscopic model confirms strong base pair metal mediated bonding for T-Hg2+-T and weaker for C-Ag+-C
Silva, Luciano Gabriel
Weber, Gerald
CHEMICAL PHYSICS LETTERS, 2022, 803

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