Intracellular non-GPI anchored isoform of CD59 is responsible for facilitating of insulin secretion from pancreatic β-cells

被引：0
|
作者：
Golec, Ewelina [1 ]
Rosberg, Rebecca [1 ]
Zhang, Enming [2 ]
Netanyah, Eitan [2 ]
Renstrom, Erik [2 ]
Kings, Ben C. [1 ]
Blom, Anna M. [1 ]
机构：
[1] Lund Univ, Sect Med Prot Chem, Dept Translat Med, Malmo, Sweden
[2] Lund Univ, Diabet Ctr, Dept Clin Sci, Malmo, Sweden
来源：
MOLECULAR IMMUNOLOGY | 2018年 / 102卷
关键词：
CD59; mutants; Intracellular function; Pancreatic islet beta cells; Insulin secretion;
D O I：
10.1016/j.molimm.2018.06.080
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
065
引用
收藏
页码：155 / 156
页数：2
相关论文
共 7 条
  • [1] A cryptic non-GPI-anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β-cells by interaction with SNARE proteins
    Golec, Ewelina
    Rosberg, Rebecca
    Zhang, Enming
    Renstrom, Erik
    Blom, Anna M.
    King, Ben C.
    FASEB JOURNAL, 2019, 33 (11): : 12425 - 12434
  • [2] Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
    Golec, Ewelina
    Ekstrom, Alexander
    Noga, Maciej
    Omar-Hmeadi, Muhmmad
    Lund, Per-Eric
    Villoutreix, Bruno O.
    Krus, Ulrika
    Wozniak, Katarzyna
    Korsgren, Olle
    Renstrom, Erik
    Barg, Sebastian
    King, Ben C.
    Blom, Anna M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 119 (24)
  • [3] Intracellular and extracellular adenosine triphosphate in regulation of insulin secretion from pancreatic β cells
    Wang, Chunjiong
    Geng, Bin
    Cui, Qinghua
    Guan, Youfei
    Yang, Jichun
    JOURNAL OF DIABETES, 2014, 6 (02) : 113 - 119
  • [4] The a3 isoform of V-ATPase regulates insulin secretion from pancreatic β-cells
    Sun-Wada, Ge-Hong
    Toyomura, Takao
    Murata, Yoshiko
    Yamamoto, Akitsugu
    Futai, Masamitsu
    Wada, Yoh
    JOURNAL OF CELL SCIENCE, 2006, 119 (21) : 4531 - 4540
  • [5] Bitter melon fruit extract enhances intracellular ATP production and insulin secretion from rat pancreatic β-cells
    Shimada, Takumi
    Kato, Fumihiro
    Dwijayanti, Dinia Rizqi
    Nagata, Takuma
    Kinoshita, Akito
    Okuyama, Tetsuya
    Nishizawa, Mikio
    Mukai, Eri
    BRITISH JOURNAL OF NUTRITION, 2022, 127 (03) : 377 - 383
  • [6] A Catalytically Inactive Lys49 PLA2 Isoform from Bothrops jararacussu venom that Stimulates Insulin Secretion in Pancreatic Beta Cells
    Fagundes, Fabio H. R.
    Aparicio, Ricardo
    dos Santos, Marcelo L.
    Diz Filho, Eduardo B. S.
    Oliveira, Simone C. B.
    Toyama, Daniela O.
    Toyama, Marcos H.
    PROTEIN AND PEPTIDE LETTERS, 2011, 18 (11): : 1133 - 1139
  • [7] Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation of insulin secretion from pancreatic β-cells
    Keane, Deirdre
    Newsholme, Philip
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2008, 36 : 955 - 958
1