Ambulatory-treated Clostridium difficile infection: a comparison of community-acquired vs. nosocomial infection

被引：12

作者：

Delate, T. ^{[1
,2
]}

Albrecht, G. ^{[3
]}

Won, K. ^{[2
]}

Jackson, A. ^{[1
]}

机构：

[1] Kaiser Permanente Colorado, Dept Pharm, Aurora, CO 80011 USA

[2] Univ Colorado, Skaggs Sch Pharm, Aurora, CO USA

[3] Exempla St Joseph Hosp, Dept Pharm, Denver, CO USA

来源：

EPIDEMIOLOGY AND INFECTION | 2015年 / 143卷 / 06期

关键词：

Antimicrobial drugs; Clostridium difficile; epidemiology; modelling; public health; EPIDEMIOLOGY;

D O I：

10.1017/S0950268814001800

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The purpose of this study was to identify the clinical outcomes of ambulatory-treated Clostridium difficile infection (CDI) and risk factors associated with community-associated CDI (CA-CDI). Adult patients diagnosed with CDI in the institutional or ambulatory-care setting between 1 April 2005 and 30 April 2011, with no other CDI diagnosis in the previous 180 days, and who purchased an ambulatory, anti-CDI agent within 7 days of CDI diagnosis were included. A total of 1201 patients were included with 914 (76%) and 287 (24%) identified with CA-CDI and nosocomial CDI (N-CDI), respectively. Patients with N-CDI were more likely to have had a recurrent CDI (P=0.043) and died from any cause (P<0.001). Patients with CA-CDI were younger, healthier, and had fewer traditional risk factors compared to patients with N-CDI. To prevent CA-CDI, clinicians should be aware that patients at risk for CA-CDI are unique from those at risk for N-CDI.

引用

页码：1225 / 1235

页数：11

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