Membrane Trafficking: Licensing a Cargo Receptor for ER Export

被引:3
|
作者
Fromme, J. Christopher [1 ]
机构
[1] Cornell Univ, Dept Mol Biol & Genet, Weill Inst Cell & Mol Biol, Ithaca, NY 14853 USA
关键词
GPI-ANCHORED PROTEINS; COPII-COATED VESICLES; ENDOPLASMIC-RETICULUM; INOSITOL DEACYLATION; TRANSPORT VESICLES; GOLGI TRANSPORT; COMPONENT; COMPLEX; EMP24P; YEAST;
D O I
10.1016/j.cub.2014.11.051
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Quality control in the endoplasmic reticulum prevents packaging of immature and misfolded proteins into vesicles, but the actual mechanisms involved in this process have not been defined for most cargos. A recent study demonstrates that the engagement of mature cargo with its receptor triggers the recruitment of a vesicle cargo adaptor.
引用
收藏
页码:R67 / R68
页数:2
相关论文
共 50 条
  • [21] WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells
    Wang, Linlin
    Liu, Hongyang
    Zhang, Xiaofei
    Song, Eli
    Wang, You
    Xu, Tao
    Li, Zonghong
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [22] WFS1 functions in ER export of vesicular cargo proteins in pancreatic β-cells
    Linlin Wang
    Hongyang Liu
    Xiaofei Zhang
    Eli Song
    You Wang
    Tao Xu
    Zonghong Li
    Nature Communications, 12
  • [23] Regulation of G protein-coupled receptor export trafficking
    Dong, Chunmin
    Filipeanu, Catalin M.
    Duvernay, Matthew T.
    Wu, Guangyu
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2007, 1768 (04): : 853 - 870
  • [24] Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites
    Su, Lu
    Zhou, Linkang
    Chen, Feng-Jung
    Wang, Huimin
    Qian, Hui
    Sheng, Yuanyuan
    Zhu, Yuangang
    Yu, Hua
    Gong, Xinqi
    Cai, Li'e
    Yang, Xuerui
    Xu, Li
    Zhao, Tong-Jin
    Li, John Zhong
    Chen, Xiao-Wei
    Li, Peng
    EMBO JOURNAL, 2019, 38 (08):
  • [25] Exploiting membrane trafficking pathways: cytoskeletal motors and cargo as targets for drug discovery
    Kamal, A
    DRUG DISCOVERY TODAY, 2003, 8 (18) : 828 - 829
  • [26] Cytoskeletal motors and cargo in membrane trafficking: opportunities for high specificity in drug intervention
    Phelps, MA
    Foraker, AB
    Swaan, PW
    DRUG DISCOVERY TODAY, 2003, 8 (11) : 494 - 502
  • [27] Cargo Abundance Influences ER Membrane Properties During Vesicle Formation
    D'Arcangelo, J. G.
    Latham, C. F.
    Miller, E. A.
    MOLECULAR BIOLOGY OF THE CELL, 2013, 24
  • [28] INTERNATIONAL LICENSING - EXPORT OF KNOWLEDGE
    BLACK, S
    BRITISH CHEMICAL ENGINEERING, 1971, 16 (4-5): : 353 - &
  • [29] The Sar1 GTPase is dispensable for COPII-dependent cargo export from the ER
    Kasberg, William
    Luong, Peter
    Hanna, Michael G.
    Minushkin, Kayla
    Tsao, Annabelle
    Shankar, Raakhee
    Block, Samuel
    Audhya, Anjon
    CELL REPORTS, 2023, 42 (06):
  • [30] Membrane turnover and receptor trafficking in regenerating axons
    Hausott, Barbara
    Klimaschewski, Lars
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2016, 43 (03) : 309 - 317