Should We Be Trying to Define Responders to Cardiac Resynchronization Therapy?

被引：20

作者：

Cleland, John G. F. ^{[1
]}

Tageldien, Ahmed ^{[1
]}

Buga, Laszlo ^{[1
]}

Wong, Kenneth ^{[1
]}

Gorcsan, John, III ^{[1
]}

机构：

[1] Univ Hull, Dept Cardiol, Castle Hill Hosp, Kingston Upon Hull HU6 7RX, N Humberside, England

来源：

JACC-CARDIOVASCULAR IMAGING | 2010年 / 3卷 / 05期

关键词：

cardiac resynchronization; echocardiography; mechanical synchrony; heart failure; BUNDLE-BRANCH BLOCK; LEFT-VENTRICULAR DYSSYNCHRONY; SHORT ATRIOVENTRICULAR DELAY; CONGESTIVE-HEART-FAILURE; INTERVENTRICULAR DELAY; RANDOMIZED-TRIAL; SCAR BURDEN; MORTALITY; ECHOCARDIOGRAPHY; PREDICTORS;

D O I：

10.1016/j.jcmg.2010.04.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

CARDIAC RESYNCHRONIZATION THERAPY (CRT) MAY PROVIDE A DRAMATIC IMPROVEMENT of symptom status and outcome in many patients with heart failure. Unfortunately, the use of current selection criteria is associated with a failure to respond on symptomatic or functional grounds of approximately 30%. Does the falling implant rate reflect a lack of enthusiasm for a treatment whose efficacy is not guaranteed-despite the certainty of risk and cost-or does it reflect the inappropriate application of other criteria of mechanical synchrony? The accompanying positions encapsulate the arguments of skeptics and supporters of the role of mechanical dyssynchrony.

引用

页码：541 / 549

页数：9

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