Changes in Intraocular Pressure During Hemodialysis: A Meta-analysis

被引:6
作者
Chen, Szu-Han [1 ]
Lu, Da-Wen [4 ]
Ku, Wan-Chen [2 ]
Chuang, Lan-Hsin [2 ]
Ferng, Shyang-Hwa [5 ]
Chen, Yi-Ju [7 ]
Lu, Yi-Hsuan [6 ]
Chai, Pony Yee-Chee [3 ]
机构
[1] Chang Gung Mem Hosp, Dept Phys Med & Rehabil, Keelung, Taiwan
[2] Chang Gung Mem Hosp, Dept Ophthalmol, Keelung, Taiwan
[3] Chang Gung Mem Hosp, Dept Pharm, Keelung, Taiwan
[4] Taipei Med Univ, Triserv Gen Hosp, Dept Ophthalmol, Taipei, Taiwan
[5] Taipei Med Univ, Cathay Gen Hosp, Dept Internal Med, Div Nephrol, Taipei, Taiwan
[6] Taipei Med Univ, Coll Publ Hlth, Sch Publ Hlth, Taipei, Taiwan
[7] Univ Pittsburgh Med Ctr UPMC Pinnacle Harrisburg, Dept Internal Med, Harrisburg, PA USA
关键词
hemodialysis; intraocular pressure; moderator; dialysate; glaucoma; PREVENTION; ELEVATION; THICKNESS; PATIENT;
D O I
10.1097/IJG.0000000000001842
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Precis: Acetate dialysate causes elevation of intradialytic intraocular pressure (IOP) and contributed to the rise of IOP in the early years of hemodialysis (HD). Glaucoma, narrow-angle, or impaired aqueous outflow is another moderator causing a rise of intradialytic IOP. Purpose: Severe IOP elevation during HD has been described in many case reports. However, the results of primary studies are conflicting. This meta-analysis examined the impact of HD on IOP and explored the potential moderators. Methods: Medline, PubMed, Embase, Web of Science, and Cochrane were systematically searched. Before-after studies reporting the change of IOP during HD were included. Intradialytic IOP changes were calculated based on 4 different definitions: highest-baseline, lowest-baseline, max-baseline, and end-baseline IOP difference. Standardized mean difference (SMD) was pooled using the random-effects model. Results: Fifty-three studies involving 1903 participants and 2845 eyes were included. Overall data pooling showed no significant rise in intradialytic IOP. However, subgroup analysis showed an intradialytic IOP rise before 1986 (SMD: 0.593; 95% confidence interval: 0.169-1.018; max-baseline IOP difference as representative; most studies using acetate dialysate), no change between 1986 and 2005 (using both acetate and bicarbonate), and a decline after 2005 (SMD: -0.222; 95% confidence interval: -0.382 to -0.063; entirely using bicarbonate). Multivariable meta-regression showed only the type of dialysate, but not publication year or other potential factors, as a significant moderator. Glaucoma was found to be another significant moderator independent of the dialysate effect in bivariate meta-regression. Conclusions: IOP elevation in the early years of HD with the use of acetate dialysate is less of a clinical problem following its substitution with bicarbonate dialysate. However, physicians should still be cautious of potential IOP changes in the HD population with glaucoma.
引用
收藏
页码:866 / 873
页数:8
相关论文
共 50 条
[41]   A Systematic Review and Meta-analysis of Systemic Antihypertensive Medications With Intraocular Pressure and Glaucoma [J].
Leung, Gareth ;
Grant, Alyssa ;
Garas, Andrew N. ;
Li, Gisele ;
Freeman, Ellen E. .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2023, 255 :7-17
[42]   The Clinical Efficacy of Different Relaxation Exercises on Intraocular Pressure Reduction: A Meta-Analysis [J].
Wu, Bing-Qi ;
Kuo, Hou-Ting ;
Hsu, Alan Y. ;
Lin, Chun-Ju ;
Lai, Chun-Ting ;
Tsai, Yi-Yu .
JOURNAL OF CLINICAL MEDICINE, 2024, 13 (09)
[43]   Intraocular pressure elevation after intravitreal triamcinolone acetonide injection: a Meta-analysis [J].
Yuksel-Elgin, Cansu ;
Elgin, Ceyhun .
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 2016, 9 (01) :139-144
[44]   Visual functional changes during acute elevation of intraocular pressure [J].
TianDe SHOU Vision Research Laboratory Center for Brain Science Research School of Life Sciences Fudan University Shanghai China .
Neuroscience Bulletin, 2006, (04) :235-238
[45]   Twenty-four-hour intraocular pressure monitoring in normotensive patients undergoing chronic hemodialysis [J].
Panagiotou, Evangelia S. ;
Liakopoulos, Vassilios ;
Giannopoulos, Theodoros ;
Voudouragkaki, Irini C. ;
Demirtzi, Paraskevi ;
Paschalinou, Eleni ;
Nikitidou, Olga ;
Kapis, Paraskevas V. ;
Konstas, Anastasios G. P. .
EUROPEAN JOURNAL OF OPHTHALMOLOGY, 2016, 26 (01) :24-29
[46]   Effect of selenium supplementation on hemodialysis patients: a meta-analysis [J].
Cheng, Qiu ;
Fan, Dandan ;
Chen, Pengyu ;
Yuan, Huaihong .
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2025, 57 (07) :2171-2179
[47]   Effects of isometric resistance exercise of the lower limbs on intraocular pressure and ocular perfusion pressure among healthy adults: A meta-analysis [J].
Li, Y. ;
Li, S. ;
Wang, Y. ;
Zhou, J. ;
Yang, J. ;
Ma, J. .
JOURNAL FRANCAIS D OPHTALMOLOGIE, 2021, 44 (10) :1596-1604
[48]   Intraocular pressure changes during cardiopulmonary bypass [J].
Sanjay O.P. ;
Prashanth P. ;
Tauro D.I. ;
Francis J. ;
Thomas A. .
Indian Journal of Thoracic and Cardiovascular Surgery, 2005, 21 (2) :157-160
[49]   Changes of Intraocular Pressure During Experimental Vitrectomy [J].
Kim, Seung Hoon ;
Choi, Kyung Seek .
CURRENT EYE RESEARCH, 2012, 37 (08) :698-703
[50]   Changes in intraocular pressure during strabismus surgery [J].
Yoo, Chungkwon ;
Chang, Mun Hee ;
Song, Jong-Suk ;
Kim, Seung-Hyun .
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE, 2010, 45 (06) :602-605