Increased prefrontal cortex connectivity during cognitive challenge assessed by fNIRS imaging

被引：57

作者：

Racz, Frigyes Samuel ^{[1
,2
]}

Mukli, Peter ^{[1
,2
]}

Nagy, Zoltan ^{[1
]}

Eke, Andras ^{[1
,2
]}

机构：

[1] Semmelweis Univ, Inst Expt Clin Res, 37-43 Tuzolto St, H-1094 Budapest, Hungary

[2] Dept Physiol, 37-43 Tuzolto St, H-1094 Budapest, Hungary

来源：

BIOMEDICAL OPTICS EXPRESS | 2017年 / 8卷 / 08期

关键词：

NEAR-INFRARED SPECTROSCOPY; STATE FUNCTIONAL CONNECTIVITY; HUMAN BRAIN; MOTOR CORTEX; BLOOD-FLOW; ALZHEIMERS-DISEASE; NETWORKS; FMRI; OXYGENATION; ACTIVATION;

D O I：

10.1364/BOE.8.003842

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In this study, functional near-infrared spectroscopy (fNIRS)and the graph theory approach were used to access the functional connectivity (FC) of the prefrontal cortex (PFC) in a resting state and during increased mental workload. For this very purpose, a pattern recognition-based test was developed, which elicited a strong response throughout the PFC during the test condition. FC parameters obtained during stimulation were found increased compared to those in a resting state after correlation based signal improvement (CBSI), which can attenuate those components of fNIRS signals which are unrelated to neural activity. These results indicate that the cognitive challenge increased the FC in the PFC and suggests a great potential in investigating FC in various cognitive states. (C) 2017 Optical Society of America

引用

页码：3842 / 3855

页数：14

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