Cryptochromes and circadian photoreception in animals

被引:35
|
作者
Partch, CL
Sancar, A
机构
[1] Dept. of Biochemistry and Biophysics, University of North Carolina, School of Medicine, Chapel Hill
来源
CIRCADIAN RHYTHMS | 2005年 / 393卷
关键词
D O I
10.1016/S0076-6879(05)93038-3
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Cryptochromes are flavin- and folate-containing blue-light photoreceptors with a high degree of similarity to DNA photolyase, which repairs ultraviolet-induced DNA damage using blue light to initiate the repair reaction. Cryptochromes play essential roles in the maintenance of circadian rhythms in mice and Drosophila, and genetic data indicate that cryptochromes function as circadian photoreceptors in these and other animals. However, the photochemical reactions carried out by cryptochromes are not known at present.
引用
收藏
页码:726 / 745
页数:20
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