Neuromodulation and Strategic Action Choice in Drosophila Aggression

被引：43
作者：
Asahina, Kenta [1 ]
机构：
[1] Salk Inst Biol Studies, Mol Neurobiol Lab, La Jolla, CA 92037 USA
来源：
ANNUAL REVIEW OF NEUROSCIENCE, VOL 40 | 2017年 / 40卷
关键词：
aggression; neuropeptides; monoamines; game theory; action choice; MODULATES MALE-AGGRESSION; MALE COURTSHIP BEHAVIOR; CAENORHABDITIS-ELEGANS; OLFACTORY NEURONS; NEURAL CIRCUITS; SUBSTANCE-P; OCTOPAMINERGIC NEURONS; NEUROPEPTIDE RECEPTORS; GENETIC ARCHITECTURE; MATERNAL AGGRESSION;
D O I：
10.1146/annurev-neuro-072116-031240
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
In this review, I discuss current knowledge and outstanding questions on the neuromodulators that influence aggressive behavior of the fruit fly Drosophila melanogaster. I first present evidence that Drosophila exchange information during an agonistic interaction and choose appropriate actions based on this information. I then discuss the influence of several biogenic amines and neuropeptides on aggressive behavior. One striking characteristic of neuromodulation is that it can configure a neural circuit dynamically, enabling one circuit to generate multiple outcomes. I suggest a consensus effect of each neuromodulatory molecule on Drosophila aggression, as well as effects of receptor proteins where relevant data are available. Lastly, I consider neuromodulation in the context of strategic action choices during agonistic interactions. Genetic components of neuromodulatory systems are highly conserved across animals, suggesting that molecular and cellular mechanisms controlling Drosophila aggression can shed light on neural principles governing action choice during social interactions.
引用
收藏
页码：51 / 75
页数：25
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