Synthesis and Rhizopus oryzae mediated enantioselective hydrolysis of α-acetoxy aryl alkyl ketones

被引：52
作者：
Demir, AS [1 ]
Hamamci, H
Tanyeli, C
Akhmedov, IM
Doganel, F
机构：
[1] Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey
[2] Middle E Tech Univ, Dept Biotechnol, TR-06531 Ankara, Turkey
[3] Middle E Tech Univ, Dept Food Engn, TR-06531 Ankara, Turkey
来源：
TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 10期
关键词：
D O I：
10.1016/S0957-4166(98)00165-7
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Mn(OAc)(3) oxidation of aromatic ketones afforded the alpha-acetoxy ketones in good yield. Selective hydrolysis of the acetoxy ketones by the fungus Rhizopus oryzae yields (R)-hydroxy ketones in high enantiomeric excess. (C) 1998 Elsevier Science Ltd. All rights reserved.
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页码：1673 / 1677
页数：5
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