HIV-Associated Vacuolar Encephalomyelopathy

被引：5

作者：

Madden, Gregory R. ^{[1
]}

Fleece, Molly E. ^{[1
]}

Gupta, Akriti ^{[2
]}

Lopes, M. Beatriz S. ^{[2
]}

Heysell, Scott K. ^{[1
]}

Arnold, Christopher J. ^{[1
]}

Wispelwey, Brian ^{[1
]}

机构：

[1] Univ Virginia Hlth Syst, Dept Med, Div Infect Dis & Int Hlth, Charlottesville, VA USA

[2] Univ Virginia Hlth Syst, Dept Pathol, Charlottesville, VA USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2019年 / 6卷 / 10期

基金：

美国国家卫生研究院;

关键词：

HIV; AIDS; vacuolar myelopathy; MYELOPATHY; AIDS; NEUROPATHY;

D O I：

10.1093/ofid/ofz366

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report a case of HIV-associated vacuolar encephalomyelopathy with progressive central nervous system dysfunction and corresponding vacuolar degeneration of the spinal cord, cranial nerves, and brain, the anatomic extent of which has not previously been described. Vacuolar myelopathy classically presents as a spinal syndrome with progressive, painless gait disturbance in the setting of advanced HIV and AIDS. Vacuolar involvement of the brain and cranial nerves, as illustrated in this case report, is a newly described variant of this condition that we term vacuolar encephalomyelopathy.

引用

页数：4

共 12 条

[1] Vacuolar myelopathy and vacuolar cerebellar leukoencephalopathy: A late complication of AIDS after highly active antiretroviral therapy-induced immune reconstitution [J].

Aboulafia, DM ;

Taylor, L .

AIDS PATIENT CARE AND STDS, 2002, 16 (12) :579-584

[2] VACUOLAR MYELOPATHY IN AIDS - A MORPHOLOGICAL ANALYSIS [J].

ARTIGAS, J ;

GROSSE, G ;

NIEDOBITEK, F .

PATHOLOGY RESEARCH AND PRACTICE, 1990, 186 (02) :228-237

[3]

Chong J, 1999, AM J NEURORADIOL, V20, P1412

[4] Pilot Study of Intravenous Immunoglobulin in HIV-Associated Myelopathy [J].

Cikurel, Katia ;

Schiff, Lauren ;

Simpson, David M. .

AIDS PATIENT CARE AND STDS, 2009, 23 (02) :75-78

[5]

DALPAN GJ, 1994, NEUROLOGY, V44, P2159

[6] Treatment of AIDS-associated myelopathy with L-methionine - A placebo-controlled study [J].

Di Rocco, A ;

Werner, P ;

Bottiglieri, T ;

Godbold, J ;

Liu, M ;

Tagliati, M ;

Scarano, A ;

Simpson, D .

NEUROLOGY, 2004, 63 (07) :1270-1275

[7]

Ernst F, 2016, SPINAL CORD SER CASE, V2, P1

[8] VACUOLAR MYELOPATHY PATHOLOGICALLY RESEMBLING SUBACUTE COMBINED DEGENERATION IN PATIENTS WITH THE ACQUIRED IMMUNODEFICIENCY SYNDROME [J].

PETITO, CK ;

NAVIA, BA ;

CHO, ES ;

JORDAN, BD ;

GEORGE, DC ;

PRICE, RW .

NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (14) :874-879

[9] Spinal MRI in vacuolar myelopathy, and correlation with histopathological findings [J].

Sartoretti-Schefer, S ;

Blattler, T ;

Wichmann, W .

NEURORADIOLOGY, 1997, 39 (12) :865-869

[10]

Siddiqi OK, 2015, MANDELL DOUGLAS BENN

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