Imaging non-motor aspects of Parkinson's disease

被引：19
作者：
Bjorklund, Anders [1 ]
Cenci, M. Angela [2 ]
机构：
[1] Lund Univ, Div Neurobiol, Wallenberg Neurosci Ctr, Lund, Sweden
[2] Lund Univ, Dept Expt Med Sci, Basal Ganglia Pathophysiol Unit, Lund, Sweden
来源：
RECENT ADVANCES IN PARKINSONS DISEASE: TRANSLATIONAL AND CLINICAL RESEARCH | 2010年 / 184卷
关键词：
Parkinson; Dementia; Depression; Sleep; Fatigue Autonomic; POSITRON-EMISSION-TOMOGRAPHY; LEWY BODIES; ALZHEIMERS-DISEASE; SEROTONIN TRANSPORTERS; DOPAMINE TRANSPORTER; DIAGNOSTIC-ACCURACY; AMYLOID DEPOSITION; DAYTIME SLEEPINESS; DEMENTIA; FATIGUE;
D O I：
10.1016/S0079-6123(10)84011-7
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
In this chapter the imaging changes associated with non-motor aspects of Parkinson's disease (PD) are reviewed. The relationship between reduced monoaminergic and cholinergic function and cognitive difficulties, depression, fatigue, sleep disorders, and dysautonomia is discussed and the relevance of Alzheimer pathology to PD dementia debated. Finally the discordance between the development of functional changes in PD and Braak staging is highlighted.
引用
收藏
页码：205 / 218
页数：14
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