Acquired hemophagocytic lymphohistiocytosis associated with multiple myeloma

被引：17

作者：

Machaczka, Maciej ^{[1
,3
]}

Vaktnas, Johan ^{[3
]}

Klimkowska, Monika ^{[2
]}

Nahi, Hareth ^{[1
]}

Hagglund, Hans ^{[1
]}

机构：

[1] Karolinska Univ, Huddinge Hosp, Hematol Ctr Karolinska, S-14186 Stockholm, Sweden

[2] Karolinska Univ, Huddinge Hosp, Dept Pathol, S-14186 Stockholm, Sweden

[3] Varberg Hosp, Dept Med, Hematol Sect, Varberg, Sweden

来源：

MEDICAL ONCOLOGY | 2011年 / 28卷 / 02期

关键词：

Hemophagocytosis; Hemophagocytic lymphohistiocytosis; Hemophagocytic syndrome; Multiple myeloma; Epilepsy; Anticonvulsants; CLINICAL-FEATURES; CHILDREN;

D O I：

10.1007/s12032-010-9484-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Acquired or secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening hyperinflammation syndrome caused mostly by various infectious agents, autoimmune disorders or malignancy. So far, only anecdotal cases of sHLH associated with multiple myeloma have been published. We provide a review of all these reports and include a previously not published case of myeloma-associated sHLH in a 59-year-old male with complex partial epilepsy. Due to aggressive course of sHLH, increased awareness is indicated in all patients with malignancies which develop unremitting fever, cytopenia and splenomegaly. Early diagnosis and immediate introduction of adequate therapy is crucial for the outcome of HLH.

引用

页码：539 / 543

页数：5

共 50 条

[21] Diagnosis and Management of Adult Malignancy-Associated Hemophagocytic Lymphohistiocytosis
Lee, Jerry C.
Logan, Aaron C.
CANCERS, 2023, 15 (06)
[22] Severe Dengue and Associated Hemophagocytic Lymphohistiocytosis in PICU
Deepanjan Bhattacharya
Suresh Kumar Angurana
Karthi Nallasamy
Rajalakshmi Iyer
Muralidharan Jayashree
The Indian Journal of Pediatrics, 2019, 86 : 1094 - 1098
[23] Severe Dengue and Associated Hemophagocytic Lymphohistiocytosis in PICU
Bhattacharya, Deepanjan
Angurana, Suresh Kumar
Nallasamy, Karthi
Iyer, Rajalakshmi
Jayashree, Muralidharan
INDIAN JOURNAL OF PEDIATRICS, 2019, 86 (12) : 1094 - 1098
[24] Hemophagocytic lymphohistiocytosis: an update for nephrologists
Filippone, Edward J.
Farber, John L.
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2016, 48 (08) : 1291 - 1304
[25] Hemophagocytic Lymphohistiocytosis
Kacer, Ayse Gonca
Celkan, Tiraje Tulin
BALKAN MEDICAL JOURNAL, 2022, 39 (05) : 309 - 317
[26] Hemophagocytic lymphohistiocytosis associated with viral infections: Diagnostic challenges and therapeutic dilemmas
Mostaza-Fernandez, J. L.
Guerra Laso, J.
Carriedo Ule, D.
Ruiz de Morales, J. M. G.
REVISTA CLINICA ESPANOLA, 2014, 214 (06): : 320 - 327
[27] Hemophagocytic lymphohistiocytosis is associated withBartonella henselaeinfection in a patient with multiple susceptibility genes
Yang, Tianjun
Mei, Qing
Zhang, Lei
Chen, Zhendong
Zhu, Chunyan
Fang, Xiaowei
Geng, Shike
Pan, Aijun
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, 2020, 19 (01)
[28] Accuracy of the criteria for hemophagocytic lymphohistiocytosis
Aksionau, Aliaksandr
Wei, Eric X.
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2020, 13 (12): : 3139 - 3148
[29] Hemophagocytic Lymphohistiocytosis: A Primer for Radiologists
Shieh, Alice C.
Guler, Ezgi
Smith, Daniel A.
Tirumani, Sree Harsha
Beck, Rose C.
Ramaiya, Nikhil H.
AMERICAN JOURNAL OF ROENTGENOLOGY, 2020, 214 (01) : W11 - W19
[30] Mechanistic Insights in Hemophagocytic Lymphohistiocytosis: Subsequent Acute Hepatic Failure in a Multiple Myeloma Patient Following Therapy with Ixazomib-Lenalidomide-Dexamethasone
Constantinescu, Catalin
Petrushev, Bobe
Rus, Ioana
Stefanescu, Horia
Frasinariu, Otilia
Margarit, Simona
Dima, Delia
Tomuleasa, Ciprian
JOURNAL OF PERSONALIZED MEDICINE, 2022, 12 (05):

← 1 2 3 4 5 →