Effects of Humic Acids, Isolated from High-Moor Pine-Peat Moss-Cotton Grass Peat on the Production of Cytokines by Mouse and Human Immunocompetent Cells and on Humoral Immune Response

被引：1

作者：

Trofimova, E. S. ^{[1
]}

Zykova, M., V ^{[2
]}

Sherstoboev, E. Yu ^{[1
]}

Danilets, M. G. ^{[1
]}

Ligacheva, A. A. ^{[1
]}

Belousov, M., V ^{[2
,3
]}

机构：

[1] Russian Acad Sci, Tomsk Res Med Ctr, ED Goldberg Res Inst Pharmacol & Regenerat Med, Tomsk, Russia

[2] Siberian State Med Univ, Minist Hlth Russia, Tomsk, Russia

[3] Natl Res Polytechnol Univ, Res Sch Chem & Biomed Technol, Tomsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2020年 / 168卷 / 05期

关键词：

humic acids; cytokines; humoral immune response; IN-VITRO; MECHANISMS;

D O I：

10.1007/s10517-020-04772-2

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

A course of treatment with humic acids extracted with sodium pyrophosphate from high-moor pine-peat moss-cotton grass peat improves humoral immune response of C57BL/6 mice, stimulates the production of TNF alpha, IL-1 beta, and IL-12 by the animal peritoneal macrophages and the production of IFN gamma and TNF alpha by donor peripheral blood mononuclears, causing no changes in the production of IL-10 in vitro.

引用

页码：651 / 653

页数：3