A prospective, randomized comparison of the acute hemodynamic effects of biventricular and left ventricular pacing with cardiac resynchronization therapy

被引:17
作者
Gold, Michael R. [1 ]
Niazi, Imran [2 ]
Giudici, Michael [3 ]
Leman, Robert B.
Sturdivant, J. Lacy
Kim, Michael H. [4 ]
Yu, Yinghong [5 ]
机构
[1] Med Univ S Carolina, Div Cardiol, Charleston, SC 29425 USA
[2] St Lukes Med Ctr, Milwaukee, WI USA
[3] Genesis Med Ctr, Davenport, IA USA
[4] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[5] Boston Sci Corp, St Paul, MN USA
关键词
Cardiac resynchronization therapy; Heart failure; Atrial pacing; Hemodynamics; dP/dt; HEART-FAILURE PATIENTS; DILATED CARDIOMYOPATHY; SYSTOLIC FUNCTION; ASYNCHRONY; TRIAL;
D O I
10.1016/j.hrthm.2010.12.039
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Cardiac resynchronization therapy (CRT) is most commonly performed with biventricular (BiV) pacing. Left ventricular (LV) only pacing is an alternative pacing configuration for CRT, but comparative studies with BiV pacing have shown inconsistent results. This may be due to differences in LV activation pattern, which could be differentially affected by atriventricular (AV) programming or atrial pacing (AP). OBJECTIVE The purpose of this study was to compare AV optimization and the effect of atrial overdrive pacing on the acute hemodynamic response of LV and BiV CRT. METHODS This study included 28 patients undergoing CRT. At implant, invasive LV dP/dt was measured by a micromanometer catheter during BiV or LV pacing in atrial sensing (AS) and AP modes at five different AV delays (AVDs), tested in randomized order. RESULTS Compared with intrinsic rhythm, CRT with AS increased LV dP/dt by 12% +/- 10% during LV pacing and by 11% +/- 11% during BiV pacing (P = .15). With atrial overdrive pacing, CRT increased LV dP/dt by 17% +/- 10% with LV pacing and by 17% +/- 11% during BiV pacing (P = NS vs. LV; P < .001 vs. AS). The optimal AVD was significantly longer with AP (LV 202 +/- 63 ms vs. 131 +/- 42 ms during AS; BiV 195 +/- 71 ms vs. 134 +/- 43 ms during AS) but did not differ between LV and BiV pacing. CONCLUSION In this study, AP increases LV dP/dt during CRT but requires a substantially longer AVD. However, the optimal AVDs were similar for LV and BiV as were the magnitudes of the responses during CRT, suggesting that programmed AVDs are interchangeable in these two configurations.
引用
收藏
页码:685 / 691
页数:7
相关论文
共 50 条
[41]   Left bundle branch pacing set to outshine biventricular pacing for cardiac resynchronization therapy? [J].
Batta, Akash ;
Hatwal, Juniali .
WORLD JOURNAL OF CARDIOLOGY, 2024, 16 (04) :186-190
[42]   Causes of impaired biventricular pacing in cardiac resynchronization devices with left ventricular sensing [J].
Haeberlin, Andreas ;
Ploux, Sylvain ;
Noel, Antoine ;
Chauvel, Remi ;
Welte, Nicolas ;
Marchand, Hugo ;
Haissaguerre, Michel ;
Ritter, Philippe ;
Eschalier, Romain ;
Bordachar, Pierre .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2020, 43 (03) :332-340
[43]   Left Bundle Branch Area Pacing versus Biventricular Pacing for Cardiac Resynchronization Therapy on Morbidity and Mortality [J].
Liang, Yixiu ;
Xiao, Zilong ;
Liu, Xi ;
Wang, Jingfeng ;
Yu, Ziqing ;
Gong, Xue ;
Lu, Hongyang ;
Yang, Shengwen ;
Gu, Min ;
Zhang, Lei ;
Li, Minghui ;
Pan, Lei ;
Li, Xiao ;
Chen, Xueying ;
Su, Yangang ;
Hua, Wei ;
Ge, Junbo .
CARDIOVASCULAR DRUGS AND THERAPY, 2024, 38 (03) :471-481
[44]   Multipoint pacing by a left ventricular quadripolar lead improves the acute hemodynamic response to CRT compared with conventional biventricular pacing at any site [J].
Zanon, Francesco ;
Baracca, Enrico ;
Pastore, Gianni ;
Marcantoni, Lina ;
Fraccaro, Chiara ;
Lanza, Daniela ;
Picariello, Claudio ;
Aggio, Silvio ;
Roncon, Loris ;
Dell'Avvocata, Fabio ;
Rigatelli, GianLuca ;
Pacetta, Domenico ;
Noventa, Franco ;
Prinzen, Frits W. .
HEART RHYTHM, 2015, 12 (05) :975-981
[45]   Sex Differences in Left Bundle Branch Area Pacing Versus Biventricular Pacing for Cardiac Resynchronization Therapy [J].
Tedrow, Usha B. ;
Miranda-Arboleda, Andres F. ;
Sauer, William H. ;
Duque, Mauricio ;
Koplan, Bruce A. ;
Marin, Jorge E. ;
Aristizabal, Julian M. ;
Nino, Cesar D. ;
Bastidas, Oriana ;
Martinez, Juan M. ;
Hincapie, Daniela ;
Hoyos, Carolina ;
Matos, Carlos D. ;
Lopez-Cabanillas, Nestor ;
Steiger, Nathaniel A. ;
Tadros, Thomas M. ;
Zei, Paul C. ;
Diaz, Juan C. ;
Romero, Jorge E. .
JACC-CLINICAL ELECTROPHYSIOLOGY, 2024, 10 (07) :1736-1749
[46]   Left Bundle Branch Area Pacing versus Biventricular Pacing for Cardiac Resynchronization Therapy on Morbidity and Mortality [J].
Yixiu Liang ;
Zilong Xiao ;
Xi Liu ;
Jingfeng Wang ;
Ziqing Yu ;
Xue Gong ;
Hongyang Lu ;
Shengwen Yang ;
Min Gu ;
Lei Zhang ;
Minghui Li ;
Lei Pan ;
Xiao Li ;
Xueying Chen ;
Yangang Su ;
Wei Hua ;
Junbo Ge .
Cardiovascular Drugs and Therapy, 2024, 38 :471-481
[47]   Acute Hemodynamic Effects of Right and Left Ventricular Lead Positions during the Implantation of Cardiac Resynchronization Therapy Defibrillators [J].
Stockinger, Jochem ;
Staier, Klaus ;
Schiebeling-Roemer, Jochen ;
Keyl, Cornelius .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2011, 34 (11) :1537-1543
[48]   A comparison of the different features of quadripolar left ventricular pacing leads to deliver cardiac resynchronization therapy [J].
Antoniadis, Antonios P. ;
Behar, Jonathan M. ;
Sieniewicz, Ben ;
Gould, Justin ;
Niederer, Steven ;
Rinaldi, Christopher A. .
EXPERT REVIEW OF MEDICAL DEVICES, 2017, 14 (09) :697-706
[49]   Alternative left ventricular pacing approaches for optimal cardiac resynchronization therapy [J].
Galand, Vincent ;
Singh, Jagmeet P. ;
Leclercq, Christophe .
HEART RHYTHM, 2019, 16 (08) :1281-1289
[50]   Left bundle branch pacing vs ventricular septal pacing for cardiac resynchronization therapy [J].
Chen, Jingjing ;
Ezzeddine, Fatima M. ;
Liu, Xiaoke ;
Vaidya, Vaibhav ;
McLeod, Christopher J. ;
Valverde, Arturo M. ;
Munoz, Freddy Del-Carpio ;
Deshmukh, Abhishek J. ;
Madhavan, Malini ;
Killu, Ammar M. ;
Mulpuru, Siva K. ;
Friedman, Paul A. ;
Cha, Yong-Mei .
HEART RHYTHM O2, 2024, 5 (03) :150-157