Multifunctional magnetite and silica-magnetite nanoparticles: Synthesis, surface activation and applications in life sciences

被引：180
作者：
del Campo, A
Sen, T
Lellouche, JP
Bruce, IJ
机构：
[1] Univ Greenwich, Sch Sci, Chatham ME6 4BT, Kent, England
[2] Univ Urbino, Inst Sci Chim, I-60129 Urbino, Italy
[3] Bar Ilan Univ, Dept Chem, IL-52900 Ramat Gan, Israel
来源：
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期
关键词：
silica-magnetite nanocomposites; surface modification; alkoxysilanes; DNA immobilisation;
D O I：
10.1016/j.jmmm.2005.01.040
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A method for the introduction of amine groups onto the surface of magnetite and silica-coated magnetite nanoparticles has been established based on the condensation of aminopropyltriethoxysilane. Amine-modified particles were grafted with an oligonucleotide and used in the capture of a complimentary sequence. The particles' efficiency at capture was observed to correlate directly with amine group surface density. (c) 2005 Elsevier B.V. All rights reserved.
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页码：33 / 40
页数：8
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