CHARACTERIZATION OF PK/PD OF ANIFROLUMAB IN PATIENTS WITH MODERATE TO SEVERE SLE

被引:3
作者
Chia, Y. L. [1 ]
Tummala, R. [2 ]
Mai, T. [3 ,4 ]
Rouse, T.
White, W. [2 ]
Morand, E. F. [5 ]
Furie, R. [6 ]
机构
[1] AstraZeneca, BioPharmaceut R&D, San Francisco, CA USA
[2] AstraZeneca, BioPharmaceut R&D, Gaithersburg, MD USA
[3] Genentech Inc, Clin Pharmacol & Modeling & Simulat, San Francisco, CA USA
[4] AstraZeneca, BioPharmaceut R&D, Gothenburg, Sweden
[5] Monash Univ, Ctr Inflammatory Dis Monash Hlth, Melbourne, Vic, Australia
[6] Zucker Sch Med Hofstra Northwell, Div Rheumatol, Great Neck, NY USA
关键词
D O I
10.1136/annrheumdis-2021-eular.1464
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
POS0688
引用
收藏
页码:590 / 591
页数:2
相关论文
共 4 条
[1]   Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus [J].
Furie, Richard ;
Khamashta, Munther ;
Merrill, Joan T. ;
Werth, Victoria P. ;
Kalunian, Kenneth ;
Brohawn, Philip ;
Illei, Gabor G. ;
Drappa, Jorn ;
Wang, Liangwei ;
Yoo, Stephen .
ARTHRITIS & RHEUMATOLOGY, 2017, 69 (02) :376-386
[2]   Type I interferon inhibitor anifrolumab in active systemic lupus erythematosus (TULIP-1) a randomised, controlled, phase 3 trial [J].
Furie, Richard A. ;
Morand, Eric F. ;
Bruce, Ian N. ;
Manzi, Susan ;
Kalunian, Kenneth C. ;
Vital, Edward M. ;
Ford, Theresa Lawrence ;
Gupta, Ramesh ;
Hiepe, Falk ;
Santiago, Mittermayer ;
Brohawn, Philip Z. ;
Berglind, Anna ;
Tummala, Raj .
LANCET RHEUMATOLOGY, 2019, 1 (04) :E208-E219
[3]  
Kuruvilla D., 2020, AAPS, V360
[4]   Trial of Anifrolumab in Active Systemic Lupus Erythematosus [J].
Morand, Eric F. ;
Furie, Richard ;
Tanaka, Yoshiya ;
Bruce, Ian N. ;
Askanase, Anca D. ;
Richez, Christophe ;
Bae, Sang-Cheol ;
Brohawn, Philip Z. ;
Pineda, Lilia ;
Berglind, Anna ;
Tummala, Raj .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (03) :211-221