Perfluorocarbon nanomaterials for photodynamic therapy

被引：30

作者：

Day, Rachael A. ^{[1
]}

Sletten, Ellen M. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE | 2021年 / 54卷

关键词：

Perfluorocarbon; Fluorous; Photodynamic therapy; Singlet oxygen; Nanoemulsion; Micelle; TUMOR HYPOXIA; OXYGEN; TRANSPORT; PHOTOSENSITIZERS; NANOPARTICLES; OVERCOME;

D O I：

10.1016/j.cocis.2021.101454

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Photodynamic therapy (PDT) is a treatment modality in which a photosensitizer is irradiated with light, producing reactive oxygen species, often via energy transfer with oxygen. As it is common for tumors to be hypoxic, methods to deliver photo sensitizer and oxygen are desirable. One such approach is the use of perfluorocarbons, molecules in which all C-H bonds are replaced with C-F bonds, to co-deliver oxygen because of the high solubility of gases in perfluorocarbons. This review highlights the benefits and limitations of several fluorinated nano material architectures for use in PDT.

引用

页数：10

共 50 条

[31] Relighting Photosensitizers by Synergistic Integration of Albumin and Perfluorocarbon for Enhanced Photodynamic Therapy [J].

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Liu, Jiaqi ;

Su, Fenhong ;

Ge, Sizhan ;

Yuan, Ahu ;

Dai, Weimin ;

Wu, Jinhui ;

Hu, Yiqiao .

ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (04) :3463-3473

[32] SOLUBILITY AND TRANSPORT PHENOMENA IN PERFLUOROCHEMICALS RELEVANT TO BLOOD SUBSTITUTION AND OTHER BIOMEDICAL APPLICATIONS [J].

RIESS, JG ;

LEBLANC, M .

PURE AND APPLIED CHEMISTRY, 1982, 54 (12) :2383-2406

[33] Oxygen carriers ("blood substitutes") - Raison d'Etre, chemistry, and some physiology [J].

Riess, JG .

CHEMICAL REVIEWS, 2001, 101 (09) :2797-2919

[34] Improving cancer therapy through the nanomaterials-assisted alleviation of hypoxia [J].

Sahu, Abhishek ;

Kwon, Inchan ;

Tae, Giyoong .

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[35] Recent Advances in 19Fluorine Magnetic Resonance Imaging with Perfl uorocarbon Emulsions [J].

Schmieder, Anne H. ;

Caruthers, Shelton D. ;

Keupp, Jochen ;

Wickline, Samuel A. ;

Lanza, Gregory M. .

ENGINEERING, 2015, 1 (04) :475-489

[36] Perfluorooctyl bromide & indocyanine green co-loaded nanoliposomes for enhanced multimodal imaging-guided phototherapy [J].

Sheng, Danli ;

Liu, Tianzhi ;

Deng, Liming ;

Zhang, Liang ;

Li, Xuelin ;

Xu, Jie ;

Hao, Lan ;

Li, Pan ;

Ran, Haitao ;

Chen, Hangrong ;

Wang, Zhigang .

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[37] Cancer nanomedicine: progress, challenges and opportunities [J].

Shi, Jinjun ;

Kantoff, Philip W. ;

Wooster, Richard ;

Farokhzad, Omid C. .

NATURE REVIEWS CANCER, 2017, 17 (01) :20-37

[38] Readily accessible multifunctional fluorous emulsions [J].

Sletten, Ellen M. ;

Swager, Timothy M. .

CHEMICAL SCIENCE, 2016, 7 (08) :5091-5097

[39] Ultrasound Triggered Tumor Oxygenation with Oxygen-Shuttle Nanoperfluorocarbon to Overcome Hypoxia-Associated Resistance in Cancer Therapies [J].

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Feng, Liangzhu ;

Liang, Chao ;

Yang, Kai ;

Liu, Zhuang .

NANO LETTERS, 2016, 16 (10) :6145-6153

[40] Acid-Activatable Transmorphic Peptide-Based Nanomaterials for Photodynamic Therapy [J].

Sun, Bingbing ;

Chang, Rui ;

Cao, Shoupeng ;

Yuan, Chengqian ;

Zhao, Luyang ;

Yang, Haowen ;

Li, Junbai ;

Yan, Xuehai ;

van Hest, Jan C. M. .

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