Shining a light on structural genomics

被引:95
作者
Kim, SH [1 ]
机构
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, EO Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA
关键词
D O I
10.1038/1334
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Determining a 'basis set' of protein folds that represent a majority of protein structures - making use of synchrotron radiation facilities - may be possible in the near future.
引用
收藏
页码:643 / 645
页数:3
相关论文
共 13 条
[1]   Protein data bank archives of three-dimensional macromolecular structures [J].
Abola, EE ;
Sussman, JL ;
Prilusky, J ;
Manning, NO .
MACROMOLECULAR CRYSTALLOGRAPHY, PT B, 1997, 277 :556-571
[2]   How many membrane proteins are there? [J].
Boyd, D ;
Schierle, C ;
Beckwith, J .
PROTEIN SCIENCE, 1998, 7 (01) :201-205
[3]   Population statistics of protein structures: Lessons from structural classifications [J].
Brenner, SE ;
Chothia, C ;
Hubbard, TJP .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 1997, 7 (03) :369-376
[4]   Assigning folds to the proteins encoded by the genome of Mycoplasma genitalium [J].
Fischer, D ;
Eisenberg, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (22) :11929-11934
[5]   A structural census of the current population of protein sequences [J].
Gerstein, M ;
Levitt, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (22) :11911-11916
[6]   Surprising similarities in structure comparison [J].
Gibrat, JF ;
Madej, T ;
Bryant, SH .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 1996, 6 (03) :377-385
[7]   Phase determination from multiwavelength anomalous diffraction measurements [J].
Hendrickson, WA ;
Ogata, CM .
MACROMOLECULAR CRYSTALLOGRAPHY, PT A, 1997, 276 :494-523
[8]   Mapping the protein universe [J].
Holm, L ;
Sander, C .
SCIENCE, 1996, 273 (5275) :595-602
[9]  
KERLAVAGE AR, 1998, TIGR MICROBIAL GENOM
[10]  
MURZIN AG, 1995, J MOL BIOL, V247, P536, DOI 10.1016/S0022-2836(05)80134-2