Identification of Barrenwort flavonoids by high-resolution tandem mass spectrometry

被引：1
|
作者：
Shevlyakova, O. A. [1 ]
Vasil'ev, K. Yu. [1 ]
Ikhalainen, A. A. [1 ]
Antokhin, A. M. [1 ]
Taranchenko, V. F. [1 ]
Goncharov, V. M. [1 ]
Mitrofanov, D. A. [1 ]
Aksenov, A. V. [1 ]
Rodin, I. A. [2 ]
Shpigun, O. A. [2 ]
机构：
[1] Signal Res Ctr, Bolshaya Olenya Ul 8, Moscow 107014, Russia
[2] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
来源：
JOURNAL OF ANALYTICAL CHEMISTRY | 2016年 / 71卷 / 08期
关键词：
Barrenwort; icariin; icaritin; icariside I and II; epimedin A; B; and C; mass spectrometry; fragmentation; CAPILLARY-ZONE-ELECTROPHORESIS; COUNTER-CURRENT CHROMATOGRAPHY; HERBA EPIMEDII; ICARIIN; MEDICINE; HPLC;
D O I：
10.1134/S106193481608013X
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Fragmentation of the main Barrenwort flavonoids-icariin, icaritin, icarisides I and II, and epimedins A and B-is studied by tandem mass spectrometry. High-resolution mass spectra of positively charged ions of these compounds are obtained under the conditions of collision-induced dissociation. Characteristic fragment ions are determined, which ensured the classification of unknown compounds as Barrenwort flavonoids. Epimedin C was isolated from raw plant material by preparative liquid chromatography; its structure was confirmed by H-1 and C-13 NMR spectra.
引用
收藏
页码：768 / 776
页数：9
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