Tumors STING Adaptive Antitumor Immunity

被引：14

作者：

Bronte, Vincenzo ^{[1
,2
]}

机构：

[1] Verona Univ Hosp, I-37134 Verona, Italy

[2] Univ Verona, Dept Pathol & Diagnost, I-37134 Verona, Italy

来源：

IMMUNITY | 2014年 / 41卷 / 05期

关键词：

CANCER;

D O I：

10.1016/j.immuni.2014.11.004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immunotherapy is revolutionizing the treatment of cancer patients, but the molecular basis for tumor immunogenicity is unclear. In this issue of Immunity, Deng et al. (2014) and Woo et al. ( 2014) provide evidence suggesting that dendritic cells detect DNA from tumor cells via the STING-mediated, cytosolic DNA sensing pathway.

引用

页码：679 / 681

页数：3

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