Monoclonal antibodies for mild-to-moderate COVID-19 in multiple sclerosis: A case series

被引：2

作者：

Moccia, Marcello ^{[1
]}

Buonomo, Antonio Riccardo ^{[1
,2
]}

Scotto, Riccardo ^{[2
]}

Viceconte, Giulio ^{[2
]}

Nobile, Mariano ^{[2
]}

Lanzillo, Roberta ^{[1
]}

Morra, Vincenzo Brescia ^{[1
]}

Gentile, Ivan ^{[2
]}

机构：

[1] Univ Naples Federico II, Multiple Sclerosis Clin Care & Res Ctr, Dept Neurosci, Naples, Italy

[2] Univ Naples Federico II, Dept Clin Med & Surg, Sect Infect Dis, Naples, Italy

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 2022年 / 439卷

关键词：

Multiple sclerosis; COVID-19; Treatment; Monoclonal antibodies;

D O I：

10.1016/j.jns.2022.120306

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We reported on five people with MS, using immunodepleting disease modifying treatments (anti-CD20 mono-clonal antibodies and sphingosine-one-phosphate modulators) and with reduced COVID-19 vaccine response, who had mild-to-moderate symptomatic COVID-19, and were treated with anti-SARS-CoV-2 monoclonal anti-bodies. In particular, we showed the possibility to use monoclonal antibodies to speed-up recovery from COVID-19 in MS, in the absence of any COVID-19 residuals or MS changes (e.g., relapses or disability).

引用

页数：4

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