Postoperative complications and functional results after subtotal gastrectomy with Billroth II reconstruction for primary gastric cancer

被引:53
作者
Pedrazzani, Corrado [1 ]
Marrelli, Daniele [1 ]
Rampone, Bernardino [1 ]
De Stefano, Alfonso [1 ]
Corso, Giovanni [1 ]
Fotia, Giuseppe [1 ]
Pinto, Enrico [1 ]
Roviello, Franco [1 ]
机构
[1] Univ Siena, Dept Human Pathol & Oncol, Unit Surg Oncol, I-53100 Siena, Italy
关键词
gastric cancer; surgical treatment; morbidity and mortality; functional results; quality of life;
D O I
10.1007/s10620-006-9655-6
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Subtotal gastrectomy is considered the preferred treatment for gastric cancer with antral location. The aim of this study was to assess the incidence of early postoperative complications and late functional results in patients who underwent subtotal gastrectomy with Billroth II reconstruction for primary gastric adenocarcinoma. The results of 310 patients were analyzed with regard to postoperative complications and death rates. Functional results as they relate to the gastric resection were evaluated in 195 disease-free patients. Of the 310 patients, 77 developed postoperative general and surgical complications (24.8%) and 13 consequently died (in-hospital mortality: 4.2%). Although infrequent (6 cases, 1.9%), anastomotic leak was the most serious complication (4 cases died during the postoperative phase). Considering functional results, weight loss continued for the first trimester after surgery, after which it stabilized. Loss of appetite was rarely observed; early after the operation the majority of patients were consuming a normal diet and regularly consumed less than five meals per day (83.6%). Dumping syndrome was uncommon and usually resolved within one year (12.3% at three months, 9.5% after one year, 5.2% after two years). On the other hand, postprandial abdominal fullness was frequently observed (43.1% at three months, 36.1% after one year, 21.3% after three years, and 16.5% after five years). Billroth II reconstruction after subtotal gastrectomy is associated with a limited risk of anastomotic complications. Anastomotic leak, although infrequent, is a life-threatening complaint and requires prompt recognition and aggressive surgical treatment. The incidence of late complications was low and the majority of patients recovered from them within one year after surgery, although the occurrence of postprandial abdominal fullness was not completely irrelevant.
引用
收藏
页码:1757 / 1763
页数:7
相关论文
共 30 条
  • [1] [Anonymous], BEITR KLIN CHIR
  • [2] Do cancer Centers designated by the National Cancer Institute have better surgical outcomes?
    Birkmeyer, NJO
    Goodney, PP
    Stukel, TA
    Hillner, BE
    Birkmeyer, JD
    [J]. CANCER, 2005, 103 (03) : 435 - 441
  • [3] Extended lymph-node dissection for gastric cancer
    Bonenkamp, JJ
    Hermans, J
    Sasako, M
    van de Velde, CJH
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (12) : 908 - 914
  • [4] Subtotal versus total gastrectomy for gastric cancer -: Five-year survival rates in a multicenter randomized Italian trial
    Bozzetti, F
    Marubini, E
    Bonfanti, G
    Miceli, R
    Piano, C
    Gennari, L
    [J]. ANNALS OF SURGERY, 1999, 230 (02) : 170 - 178
  • [5] Lymph-node dissection for gastric cancer
    Brennan, MF
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (12) : 956 - 958
  • [6] RECONSTRUCTION AFTER GASTRECTOMY AND QUALITY-OF-LIFE
    BUHL, K
    LEHNERT, T
    SCHLAG, P
    HERFARTH, C
    [J]. WORLD JOURNAL OF SURGERY, 1995, 19 (04) : 558 - 564
  • [7] BUHL K, 1990, EUR J SURG ONCOL, V16, P404
  • [8] Patient survival after D1 and D2 resections for gastric cancer:: long-term results of the MRC randomized surgical trial
    Cuschieri, A
    Weeden, S
    Fielding, J
    Bancewicz, J
    Craven, J
    Joypaul, V
    Sydes, M
    Fayers, P
    [J]. BRITISH JOURNAL OF CANCER, 1999, 79 (9-10) : 1522 - 1530
  • [9] Total or subtotal gastrectomy for gastric carcinoma? A study of quality of life
    Davies, J
    Johnston, D
    Sue-Ling, H
    Young, S
    May, J
    Griffith, J
    Miller, G
    Martin, I
    [J]. WORLD JOURNAL OF SURGERY, 1998, 22 (10) : 1048 - 1055
  • [10] Subtotal versus total gastrectomy for T3 adenocarcinoma of the antrum
    Giovanni de Manzoni
    Giuseppe Verlato
    Franco Roviello
    Alberto Di Leo
    Daniele Marrelli
    Paolo Morgagni
    Felice Pasini
    Luca Saragoni
    Anna Tomezzoli
    [J]. Gastric Cancer, 2003, 6 (4) : 237 - 242