Relevance of angiotensin II-induced aortic pathologies in mice to human aortic aneurysms

被引：45
|
作者：
Bruemmer, Dennis [1 ]
Daugherty, Alan [1 ]
Lu, Hong [1 ]
Rateri, Debra L. [1 ]
机构：
[1] Univ Kentucky, Saha Cardiovasc Res Ctr, Lexington, KY USA
来源：
ANIMAL MODELS: THEIR VALUE IN PREDICTING DRUG EFFICACY AND TOXICITY | 2011年 / 1245卷
基金：
美国国家卫生研究院;
关键词：
aortic aneurysms; angiotensin II; mouse; human; DEFICIENCY;
D O I：
10.1111/j.1749-6632.2011.06332.x
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Angiotensin II infusion in mice promotes abdominal and thoracic aortic aneurysms, which provides a feasible approach to study the mechanisms of these two distinct diseases.
引用
收藏
页码：7 / 10
页数：4
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