Relevance of angiotensin II-induced aortic pathologies in mice to human aortic aneurysms

被引：47

作者：

Bruemmer, Dennis ^{[1
]}

Daugherty, Alan ^{[1
]}

Lu, Hong ^{[1
]}

Rateri, Debra L. ^{[1
]}

机构：

[1] Univ Kentucky, Saha Cardiovasc Res Ctr, Lexington, KY USA

来源：

ANIMAL MODELS: THEIR VALUE IN PREDICTING DRUG EFFICACY AND TOXICITY | 2011年 / 1245卷

基金：

美国国家卫生研究院;

关键词：

aortic aneurysms; angiotensin II; mouse; human; DEFICIENCY;

D O I：

10.1111/j.1749-6632.2011.06332.x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Angiotensin II infusion in mice promotes abdominal and thoracic aortic aneurysms, which provides a feasible approach to study the mechanisms of these two distinct diseases.

引用

页码：7 / 10

页数：4

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