Polybrominated diphenyl ethers in human serum and sperm quality

被引：100

作者：

Akutsu, K. ^{[1
,2
]}

Takatori, S. ^{[1
]}

Nozawa, S. ^{[3
]}

Yoshiike, M. ^{[3
]}

Nakazawa, H. ^{[4
]}

Hayakawa, K. ^{[2
]}

Makino, T. ^{[5
]}

Iwamoto, T. ^{[3
]}

机构：

[1] Osaka Prefectural Inst Publ Hlth, Div Food Chem, Higashinari Ku, Osaka 5370025, Japan

[2] Kanazawa Univ, Grad Sch Nat Sci & Technol, Kanazawa, Ishikawa 9201192, Japan

[3] St Marianna Univ, Sch Med, Dept Urol, Miyamae Ku, Kanagawa 2168511, Japan

[4] Hoshi Univ, Dept Analyt Chem, Shinagawa Ku, Tokyo 1428501, Japan

[5] Tokai Univ, Dept Obstet & Gynecol, Sch Med, Kanagawa 2591143, Japan

来源：

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 2008年 / 80卷 / 04期

关键词：

polybrominated diphenyl ethers; flame retardants; human serum; sperm;

D O I：

10.1007/s00128-008-9370-4

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Polybrominated diphenyl ethers (PBDEs) are widely used flame retardants; currently, they are identified as ubiquitous environmental contaminants. Several studies indicate that PBDEs might affect male fertility. We present the results of a pilot study on the relationship between human serum PBDEs and sperm quality. The PBDE levels in Japan are comparable to those found in European countries. Strong inverse correlations were observed between the serum concentration of 2,2',4,4',5,5'-hexabromodiphenyl ether and sperm concentration (r = -0.841, p = 0.002) and testis size (r = -0.764, p = 0.01). Extensive studies on the relationship between PBDEs and sperm quality are required.

引用

页码：345 / 350

页数：6

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