Concise Synthesis of Hydroxy β-Methyl Fatty Acid Ethyl Esters

被引：0

作者：

Sakai, Yuki ^{[1
]}

Asakura, Yukiko ^{[1
]}

Morita, Mitsuhiro ^{[2
]}

Takahashi, Takashi ^{[1
]}

机构：

[1] Yokohama Univ Pharm, Dept Pharmaceut Sci, Totsuka Ku, 60 Matano Cho, Yokohama, Kanagawa 2450066, Japan

[2] Kobe Univ, Dept Biol, Grad Sch Sci, Kobe, Hyogo 6578501, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2017年 / 65卷 / 12期

关键词：

beta-methyl fatty acid; chemical synthesis; Johnson-Claisen rearrangement; hydroxy fatty acid; PHYTANIC ACID; HUMAN HEALTH;

D O I：

10.1248/cpb.c17-00637

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Hydroxy beta-methyl fatty acid ethyl esters bearing different carbon chain lengths and varying hydroxyl group positions were successfully synthesized from symmetric diols. These fatty acid derivatives are useful intermediates of chemical probes for metabolic analyses of fatty acid.

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页码：1195 / 1198

页数：4

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